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Near infrared imaging of Mer tyrosine kinase (MerTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease
The receptor tyrosine kinase Mer (MERTK) is a promising drug target in cancer, where it can influence the metastasis-promoting signaling of both tumor cells and immune cells alike; however, no small molecule probes currently exist to selectively image Mer. In this work, we design and synthesize a se...
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| Опубликовано в: : | Chem Commun (Camb) |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736449/ https://ncbi.nlm.nih.gov/pubmed/29185561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07581b |
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