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Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis

Phagocytosis of apoptotic cells by macrophages and spent photoreceptor outer segments (POS) by retinal pigment epithelial (RPE) cells requires several proteins, including MerTK receptors and associated Gas6 and protein S ligands. In the retina, POS phagocytosis is rhythmic, and MerTK is activated pr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Law, Ah-Lai, Parinot, Célia, Chatagnon, Jonathan, Gravez, Basile, Sahel, José-Alain, Bhattacharya, Shomi S., Nandrot, Emeline F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335232/
https://ncbi.nlm.nih.gov/pubmed/25538233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628297
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