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Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis

Phagocytosis of apoptotic cells by macrophages and spent photoreceptor outer segments (POS) by retinal pigment epithelial (RPE) cells requires several proteins, including MerTK receptors and associated Gas6 and protein S ligands. In the retina, POS phagocytosis is rhythmic, and MerTK is activated pr...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Law, Ah-Lai, Parinot, Célia, Chatagnon, Jonathan, Gravez, Basile, Sahel, José-Alain, Bhattacharya, Shomi S., Nandrot, Emeline F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335232/
https://ncbi.nlm.nih.gov/pubmed/25538233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628297
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