MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

The acute inflammatory response requires a coordinated resolution program to prevent excessive inflammation, repair collateral damage, and restore tissue homeostasis, and failure of this response contributes to the pathology of numerous chronic inflammatory diseases. Resolution is mediated in part b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cai, Bishuang, Thorp, Edward B., Doran, Amanda C., Subramanian, Manikandan, Sansbury, Brian E., Lin, Chyuan-Sheng, Spite, Matthew, Fredman, Gabrielle, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988577/
https://ncbi.nlm.nih.gov/pubmed/27199481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524292113
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