Resolvin D1 promotes efferocytosis in aging by limiting senescent cell-induced MerTK cleavage

Inflammation-resolution is mediated by the balance between specialized pro-resolving mediators (SPMs) like resolvin D1 (RvD1) and pro-inflammatory factors, like leukotriene B(4) (LTB(4)). A key cellular process of inflammation-resolution is efferocytosis. Aging is associated with defective inflammat...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Rymut, Nicholas, Heinz, Justin, Sadhu, Sudeshna, Hosseini, Zeinab, Riley, Colin O., Marinello, Michael, Maloney, Jackson, MacNamara, Katherine C., Spite, Matthew, Fredman, Gabrielle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956736/
https://ncbi.nlm.nih.gov/pubmed/31914705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902126R
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