MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair after Myocardial Ischemia Reperfusion Injury

RATIONALE: Clinical benefits of reperfusion after myocardial infarction (MI) are offset by maladaptive innate immune cell function and therapeutic interventions are lacking. OBJECTIVE: We sought to test the significance of phagocytic clearance by resident and recruited phagocytes after myocardial is...

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Veröffentlicht in:Circ Res
Hauptverfasser: DeBerge, Matthew, Yeap, Xin Yi, Dehn, Shirley, Zhang, Shuang, Grigoryeva, Lubov, Misener, Sol, Procissi, Daniel, Zhou, Xin, Lee, Daniel C., Muller, William A., Luo, Xunrong, Rothlin, Carla, Tabas, Ira, Thorp, Edward B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623080/
https://ncbi.nlm.nih.gov/pubmed/28851810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311327
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