Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is emerging as a leading cause of chronic liver disease. However, therapeutic options are limited by incomplete understanding of mechanisms of NASH fibrosis, which is mediated by activation of hepatic stellate cells (HSCs). In humans, human genetic studies have sh...

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Pubblicato in:Cell Metab
Autori principali: Cai, Bishuang, Dongiovanni, Paola, Corey, Kathleen E., Wang, Xiaobo, Shmarakov, Igor O., Zheng, Ze, Kasikara, Canan, Davra, Viralkumar, Meroni, Marica, Chung, Raymond T., Rothlin, Carla, Schwabe, Robert F., Blaner, William S., Birge, Raymond B., Valenti, Luca, Tabas, Ira
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004886/
https://ncbi.nlm.nih.gov/pubmed/31839486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.11.013
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