Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is emerging as a leading cause of chronic liver disease. However, therapeutic options are limited by incomplete understanding of mechanisms of NASH fibrosis, which is mediated by activation of hepatic stellate cells (HSCs). In humans, human genetic studies have sh...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Cai, Bishuang, Dongiovanni, Paola, Corey, Kathleen E., Wang, Xiaobo, Shmarakov, Igor O., Zheng, Ze, Kasikara, Canan, Davra, Viralkumar, Meroni, Marica, Chung, Raymond T., Rothlin, Carla, Schwabe, Robert F., Blaner, William S., Birge, Raymond B., Valenti, Luca, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004886/
https://ncbi.nlm.nih.gov/pubmed/31839486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.11.013
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