Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis

Phagocytosis of apoptotic cells by macrophages and spent photoreceptor outer segments (POS) by retinal pigment epithelial (RPE) cells requires several proteins, including MerTK receptors and associated Gas6 and protein S ligands. In the retina, POS phagocytosis is rhythmic, and MerTK is activated pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Law, Ah-Lai, Parinot, Célia, Chatagnon, Jonathan, Gravez, Basile, Sahel, José-Alain, Bhattacharya, Shomi S., Nandrot, Emeline F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2015
Pynciau:
Neurobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335232/
https://ncbi.nlm.nih.gov/pubmed/25538233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628297
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