“RAS”ling β cells to proliferate for diabetes: why do we need MEN?

Por García-Ocaña, Adolfo, Stewart, Andrew F.
Publicado em 2014

Mechanisms in the adaptation of maternal β-cells during pregnancy

Por Ernst, Sara, Demirci, Cem, Valle, Shelley, Velazquez-Garcia, Silvia, Garcia-Ocaña, Adolfo
Publicado em 2011

Anti-incretin, Anti-proliferative Action of Dopamine on β-Cells

Por Maffei, Antonella, Segal, Ann Marie, Alvarez-Perez, Juan Carlos, Garcia-Ocaña, Adolfo, Harris, Paul E.
Publicado no Mol Endocrinol (2015)

Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand (RANKL) Pathway

Por Kondegowda, Nagesha Guthalu, Fenutria, Rafael, Pollack, Ilana, Orthofer, Michael, Garcia-Ocaña, Adolfo, Penninger, Josef, Vasavada, Rupangi C.
Publicado no Cell Metab (2015)

Human β-Cell Proliferation and Intracellular Signaling Part 2: Still Driving in the Dark Without a Road Map

Por Bernal-Mizrachi, Ernesto, Kulkarni, Rohit N., Scott, Donald K., Mauvais-Jarvis, Franck, Stewart, Andrew F., Garcia-Ocaña, Adolfo
Publicado em 2014

Hepatocyte Growth Factor Is a Novel Stimulator of Glucose Uptake and Metabolism in Skeletal Muscle Cells

Por Perdomo, German, Martinez-Brocca, Maria A., Bhatt, Bankim A., Brown, Nicholas F., O'Doherty, Robert M., Garcia-Ocaña, Adolfo
Publicado em 2008

Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

Por Blouin, Cédric M., Prado, Cécilia, Takane, Karen K., Lasnier, Françoise, Garcia-Ocana, Adolfo, Ferré, Pascal, Dugail, Isabelle, Hajduch, Eric
Publicado em 2010

Glucose Infusion in Mice: A New Model to Induce β-Cell Replication

Por Alonso, Laura C., Yokoe, Takuya, Zhang, Pili, Scott, Donald K., Kim, Seung K., O’Donnell, Christopher P., Garcia-Ocaña, Adolfo
Publicado em 2007

Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Por Gao, Jie, He, Jinhan, Shi, Xiongjie, Stefanovic-Racic, Maja, Xu, Meishu, O’Doherty, Robert Martin, Garcia-Ocana, Adolfo, Xie, Wen
Publicado em 2012

Human β-Cell Proliferation and Intracellular Signaling: Part 3

Por Stewart, Andrew F., Hussain, Mehboob A., García-Ocaña, Adolfo, Vasavada, Rupangi C., Bhushan, Anil, Bernal-Mizrachi, Ernesto, Kulkarni, Rohit N.
Publicado no Diabetes (2015)

Parathyroid Hormone-Related Peptide (1-36) Enhances Beta Cell Regeneration and Increases Beta Cell Mass in a Mouse Model of Partial Pancreatectomy

Por Mozar, Anaïs, Lin, Hugo, Williams, Katoura, Chin, Connie, Li, Rosemary, Kondegowda, Nagesha Guthalu, Stewart, Andrew F., Garcia-Ocaña, Adolfo, Vasavada, Rupangi Chhaya
Publicado no PLoS One (2016)

Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets

Por Fiaschi-Taesch, Nathalie M., Berman, Dora M., Sicari, Brian M., Takane, Karen K., Garcia-Ocaña, Adolfo, Ricordi, Camillo, Kenyon, Norma S., Stewart, Andrew F.
Publicado em 2008

Free Fatty Acids Block Glucose-Induced β-Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18

Por Pascoe, Jordan, Hollern, Douglas, Stamateris, Rachel, Abbasi, Munira, Romano, Lia C., Zou, Baobo, O’Donnell, Christopher P., Garcia-Ocana, Adolfo, Alonso, Laura C.
Publicado em 2012

Intermittent Hypoxia Causes Insulin Resistance in Lean Mice Independent of Autonomic Activity

Por Iiyori, Nao, Alonso, Laura C., Li, Jianguo, Sanders, Mark H., Garcia-Ocana, Adolfo, O'Doherty, Robert M., Polotsky, Vsevolod Y., O'Donnell, Christopher P.
Publicado em 2007

Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic β-cell replication in mice

Por Yokoe, Takuya, Alonso, Laura C, Romano, Lia C, Rosa, Taylor C, O'Doherty, Robert M, Garcia-Ocana, Adolfo, Minoguchi, Kenji, O'Donnell, Christopher P
Publicado em 2008

Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice

Por Watanabe, Yoshio, Singamsetty, Srikanth, Zou, Baobo, Guo, Lanping, Stefanovski, Darko, Alonso, Laura C., Garcia-Ocana, Adolfo, O’Donnell, Christopher P., McVerry, Bryan J.
Publicado em 2013

Parathyroid Hormone-Related Protein for the Treatment of Postmenopausal Osteoporosis: Defining the Maximal Tolerable Dose

Por Horwitz, Mara J., Tedesco, Mary Beth, Garcia-Ocaña, Adolfo, Sereika, Susan M., Prebehala, Linda, Bisello, Alessandro, Hollis, Bruce W., Gundberg, Caren M., Stewart, Andrew F.
Publicado em 2010

Hepatocyte Growth Factor/c-Met Signaling Is Required for β-Cell Regeneration

Por Alvarez-Perez, Juan Carlos, Ernst, Sara, Demirci, Cem, Casinelli, Gabriella P., Mellado-Gil, Jose Manuel D., Rausell-Palamos, Francisco, Vasavada, Rupangi C., Garcia-Ocaña, Adolfo
Publicado em 2014

Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

Por Demirci, Cem, Ernst, Sara, Alvarez-Perez, Juan C., Rosa, Taylor, Valle, Shelley, Shridhar, Varsha, Casinelli, Gabriella P., Alonso, Laura C., Vasavada, Rupangi C., García-Ocana, Adolfo
Publicado em 2012

Hepatocyte Growth Factor Ameliorates Hyperglycemia and Corrects β-Cell Mass in IRS2-Deficient Mice

Por Alvarez-Perez, Juan C., Rosa, Taylor C., Casinelli, Gabriella P., Valle, Shelley R., Lakshmipathi, Jayalakshmi, Rosselot, Carolina, Rausell-Palamos, Francisco, Vasavada, Rupangi C., García-Ocaña, Adolfo
Publicado no Mol Endocrinol (2014)