Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Estrogen sulfotransferase (EST), the enzyme responsible for the sulfonation and inactivation of estrogens, plays an important role in estrogen homeostasis. In this study, we showed that induction of hepatic Est is a common feature of type 2 diabetes. Loss of Est in female mice improved metabolic fun...

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Detalhes bibliográficos
Main Authors: Gao, Jie, He, Jinhan, Shi, Xiongjie, Stefanovic-Racic, Maja, Xu, Meishu, O’Doherty, Robert Martin, Garcia-Ocana, Adolfo, Xie, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357292/
https://ncbi.nlm.nih.gov/pubmed/22438574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1152
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