Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Estrogen sulfotransferase (EST), the enzyme responsible for the sulfonation and inactivation of estrogens, plays an important role in estrogen homeostasis. In this study, we showed that induction of hepatic Est is a common feature of type 2 diabetes. Loss of Est in female mice improved metabolic fun...

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Bibliographic Details
Main Authors: Gao, Jie, He, Jinhan, Shi, Xiongjie, Stefanovic-Racic, Maja, Xu, Meishu, O’Doherty, Robert Martin, Garcia-Ocana, Adolfo, Xie, Wen
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357292/
https://ncbi.nlm.nih.gov/pubmed/22438574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1152
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