Free Fatty Acids Block Glucose-Induced β-Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18

Pancreatic β-cell proliferation is infrequent in adult humans and is not increased in type 2 diabetes despite obesity and insulin resistance, suggesting the existence of inhibitory factors. Free fatty acids (FFAs) may influence proliferation. In order to test whether FFAs restrict β-cell proliferati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pascoe, Jordan, Hollern, Douglas, Stamateris, Rachel, Abbasi, Munira, Romano, Lia C., Zou, Baobo, O’Donnell, Christopher P., Garcia-Ocana, Adolfo, Alonso, Laura C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282818/
https://ncbi.nlm.nih.gov/pubmed/22338094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0991
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados