Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice

OBJECTIVES: The development of hyperglycemia and the use of early parenteral feeding are associated with poor outcomes in critically ill patients. We therefore examined the impact of exogenous glucose administration on the integrated metabolic function of endotoxemic mice using our recently develope...

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Main Authors: Watanabe, Yoshio, Singamsetty, Srikanth, Zou, Baobo, Guo, Lanping, Stefanovski, Darko, Alonso, Laura C., Garcia-Ocana, Adolfo, O’Donnell, Christopher P., McVerry, Bryan J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691245/
https://ncbi.nlm.nih.gov/pubmed/23826335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067716
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