Stimulation of the endogenous incretin glucose-dependent insulinotropic peptide by enteral dextrose improves glucose homeostasis and inflammation in murine endotoxemia

Loss of glucose homeostasis during sepsis is associated with increased organ dysfunction and higher mortality. Novel therapeutic strategies to promote euglycemia in sepsis are needed. We have previously shown that early low-level intravenous (IV) dextrose suppresses pancreatic insulin secretion and...

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Publicado no:Transl Res
Main Authors: SHAH, FARAAZ ALI, SINGAMSETTY, SRIKANTH, GUO, LANPING, CHUAN, BYRON W., MCDONALD, SHERIE, COOPER, BRYCE A., O’DONNELL, BRETT J., STEFANOVSKI, DARKO, WICE, BURTON, ZHANG, YINGZE, O’DONNELL, CHRISTOPHER P., MCVERRY, BRYAN J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826869/
https://ncbi.nlm.nih.gov/pubmed/29222967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.11.001
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