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Stimulation of the endogenous incretin glucose-dependent insulinotropic peptide by enteral dextrose improves glucose homeostasis and inflammation in murine endotoxemia

Loss of glucose homeostasis during sepsis is associated with increased organ dysfunction and higher mortality. Novel therapeutic strategies to promote euglycemia in sepsis are needed. We have previously shown that early low-level intravenous (IV) dextrose suppresses pancreatic insulin secretion and...

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Détails bibliographiques
Publié dans:Transl Res
Auteurs principaux: SHAH, FARAAZ ALI, SINGAMSETTY, SRIKANTH, GUO, LANPING, CHUAN, BYRON W., MCDONALD, SHERIE, COOPER, BRYCE A., O’DONNELL, BRETT J., STEFANOVSKI, DARKO, WICE, BURTON, ZHANG, YINGZE, O’DONNELL, CHRISTOPHER P., MCVERRY, BRYAN J.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826869/
https://ncbi.nlm.nih.gov/pubmed/29222967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.11.001
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