Recent Insights into the HIV/AIDS Pandemic

Por Becerra, Juan C., Bildstein, Lukas S., Gach, Johannes S.
Publicado no Microb Cell (2016)

Anti-p21 autoantibodies detected in colorectal cancer patients: A proof of concept study

Por Bishehsari, Faraz, Gach, Johannes S, Akagi, Naomi, Webber, Molly K, Bauer, Jessica, Jung, Barbara H
Publicado no Oncoimmunology (2014)

Relationship between Vaccine-Induced Antibody Capture of Infectious Virus and Infection Outcomes following Repeated Low-Dose Rectal Challenges with Simian Immunodeficiency Virus SI...

Por Gach, Johannes S., Venzon, David, Vaccari, Monica, Keele, Brandon F., Franchini, Genoveffa, Forthal, Donald N.
Publicado no J Virol (2016)

Proline Is Not Uniquely Capable of Providing the Pivot Point for Domain Swapping in 2G12, a Broadly Neutralizing Antibody against HIV-1

Por Gach, Johannes S., Furtmüller, Paul G., Quendler, Heribert, Messner, Paul, Wagner, Ralf, Katinger, Hermann, Kunert, Renate
Publicado em 2010

Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope

Por Stanfield, Robyn L., Julien, Jean-Philippe, Pejchal, Robert, Gach, Johannes S., Zwick, Michael B., Wilson, Ian A.
Publicado em 2011

A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens

Por Dotsey, Emmanuel Y., Gorlani, Andrea, Ingale, Sampat, Achenbach, Chad J., Forthal, Donald N., Felgner, Philip L., Gach, Johannes S.
Publicado no PLoS One (2015)

Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis

Por Gach, Johannes S., Bouzin, Margaux, Wong, Marcus P., Chromikova, Veronika, Gorlani, Andrea, Yu, Kuan-Ting, Sharma, Brijesh, Gratton, Enrico, Forthal, Donald N.
Publicado no PLoS Pathog (2017)

Enhanced In Vitro Transcytosis of Simian Immunodeficiency Virus Mediated by Vaccine-Induced Antibody Predicts Transmitted/Founder Strain Number After Rectal Challenge

Por Gupta, Sandeep, Pegu, Poonam, Venzon, David J., Gach, Johannes S., Ma, Zhong-Min, Landucci, Gary, Miller, Christopher J., Franchini, Genoveffa, Forthal, Donald N.
Publicado no J Infect Dis (2015)

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

Por Walker, Laura M., Simek, Melissa D., Priddy, Frances, Gach, Johannes S., Wagner, Denise, Zwick, Michael B., Phogat, Sanjay K., Poignard, Pascal, Burton, Dennis R.
Publicado em 2010

HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans

Por Williams, Katherine L., Cortez, Valerie, Dingens, Adam S., Gach, Johannes S., Rainwater, Stephanie, Weis, Julie F., Chen, Xuemin, Spearman, Paul, Forthal, Donald N., Overbaugh, Julie
Publicado no EBioMedicine (2015)

Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

Por Song, Likai, Sun, Zhen-Yu J., Coleman, Kate E., Zwick, Michael B., Gach, Johannes S., Wang, Jia-huai, Reinherz, Ellis L., Wagner, Gerhard, Kim, Mikyung
Publicado em 2009

HIV-1 Specific Antibody Titers and Neutralization among Chronically Infected Patients on Long-Term Suppressive Antiretroviral Therapy (ART): A Cross-Sectional Study

Por Gach, Johannes S., Achenbach, Chad J., Chromikova, Veronika, Berzins, Baiba, Lambert, Nina, Landucci, Gary, Forthal, Donald N., Katlama, Christine, Jung, Barbara H., Murphy, Robert L.
Publicado em 2014

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

Por Pejchal, Robert, Gach, Johannes S., Brunel, Florence M., Cardoso, Rosa M., Stanfield, Robyn L., Dawson, Philip E., Burton, Dennis R., Zwick, Michael B., Wilson, Ian A.
Publicado em 2009

A Human Antibody to the CD4 Binding Site of gp120 Capable of Highly Potent but Sporadic Cross Clade Neutralization of Primary HIV-1

Por Gach, Johannes S., Quendler, Heribert, Tong, Tommy, Narayan, Kristin M., Du, Sean X., Whalen, Robert G., Binley, James M., Forthal, Donald N., Poignard, Pascal, Zwick, Michael B.
Publicado em 2013

Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM

Por Chromikova, Veronika, Mader, Alexander, Hofbauer, Stefan, Göbl, Christoph, Madl, Tobias, Gach, Johannes S., Bauernfried, Stefan, Furtmüller, Paul G., Forthal, Donald N., Mach, Lukas, Obinger, Christian, Kunert, Renate
Publicado no Biochim Biophys Acta (2015)

Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants

Por Loos, Andreas, Gach, Johannes S., Hackl, Thomas, Maresch, Daniel, Henkel, Theresa, Porodko, Andreas, Bui-Minh, Duc, Sommeregger, Wolfgang, Wozniak-Knopp, Gordana, Forthal, Donald N., Altmann, Friedrich, Steinkellner, Herta, Mach, Lukas
Publicado no Proc Natl Acad Sci U S A (2015)

4E10-Resistant HIV-1 Isolated from Four Subjects with Rare Membrane-Proximal External Region Polymorphisms

Por Nakamura, Kyle J., Gach, Johannes S., Jones, Laura, Semrau, Katherine, Walter, Jan, Bibollet-Ruche, Frederic, Decker, Julie M., Heath, Laura, Decker, William D., Sinkala, Moses, Kankasa, Chipepo, Thea, Donald, Mullins, James, Kuhn, Louise, Zwick, Michael B., Aldrovandi, Grace M.
Publicado em 2010

HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects

Por Gach, Johannes S., Gorlani, Andrea, Dotsey, Emmanuel Y., Becerra, Juan C., Anderson, Chase T. M., Berzins, Baiba, Felgner, Philip L., Forthal, Donald N., Deeks, Steven G., Wilkin, Timothy J., Casazza, Joseph P., Koup, Richard A., Katlama, Christine, Autran, Brigitte, Murphy, Robert L., Achenbach, Chad J.
Publicado no PLoS One (2016)

The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells

Por Gupta, Sandeep, Gach, Johannes S., Becerra, Juan C., Phan, Tran B., Pudney, Jeffrey, Moldoveanu, Zina, Joseph, Sarah B., Landucci, Gary, Supnet, Medalyn Jude, Ping, Li-Hua, Corti, Davide, Moldt, Brian, Hel, Zdenek, Lanzavecchia, Antonio, Ruprecht, Ruth M., Burton, Dennis R., Mestecky, Jiri, Anderson, Deborah J., Forthal, Donald N.
Publicado em 2013

Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells

Por Gupta, Sandeep, Gach, Johannes S., Becerra, Juan C., Phan, Tran B., Pudney, Jeffrey, Moldoveanu, Zina, Joseph, Sarah B., Landucci, Gary, Supnet, Medalyn Jude, Ping, Li-Hua, Corti, Davide, Moldt, Brian, Hel, Zdenek, Lanzavecchia, Antonio, Ruprecht, Ruth M., Burton, Dennis R., Mestecky, Jiri, Anderson, Deborah J., Forthal, Donald N.
Publicado em 2013