Relationship between Vaccine-Induced Antibody Capture of Infectious Virus and Infection Outcomes following Repeated Low-Dose Rectal Challenges with Simian Immunodeficiency Virus SIVmac251

Antibodies are known to enhance in vitro infection by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). We measured the ability of antibodies induced by ALVAC-SIV/gp120 vaccination, given with alum or MF59 adjuvant, to capture infectious SIVmac251 and determined the associa...

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Vydáno v:J Virol
Hlavní autoři: Gach, Johannes S., Venzon, David, Vaccari, Monica, Keele, Brandon F., Franchini, Genoveffa, Forthal, Donald N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021405/
https://ncbi.nlm.nih.gov/pubmed/27440881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00812-16
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