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The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells

The mechanisms by which human immunodeficiency virus type 1 (HIV-1) crosses mucosal surfaces to establish infection are unknown. Acidic genital secretions of HIV-1-infected women contain HIV-1 likely coated by antibody. We found that the combination of acidic pH and Env-specific IgG, including that...

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Detalhes bibliográficos
Main Authors: Gupta, Sandeep, Gach, Johannes S., Becerra, Juan C., Phan, Tran B., Pudney, Jeffrey, Moldoveanu, Zina, Joseph, Sarah B., Landucci, Gary, Supnet, Medalyn Jude, Ping, Li-Hua, Corti, Davide, Moldt, Brian, Hel, Zdenek, Lanzavecchia, Antonio, Ruprecht, Ruth M., Burton, Dennis R., Mestecky, Jiri, Anderson, Deborah J., Forthal, Donald N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836734/
https://ncbi.nlm.nih.gov/pubmed/24278022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003776
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