FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects

מאת Lagorce, David, Sperandio, Olivier, Galons, Hervé, Miteva, Maria A, Villoutreix, Bruno O
יצא לאור 2008

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

מאת Troadec, Samuel, Blairvacq, Mélina, Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Berthou, Christian
הוצא לאור ב J Biomed Sci (2015)

Antiprion Drugs as Chemical Tools to Uncover Mechanisms of Prion Propagation

מאת Tribouillard, Déborah, Gug, Fabienne, Galons, Hervé, Bach, Stéphane, Saupe, Sven J, Blondel, Marc
יצא לאור 2007

A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back...

מאת El Hage, Krystel, Piquemal, Jean-Philip, Oumata, Nassima, Meijer, Laurent, Galons, Hervé, Gresh, Nohad
הוצא לאור ב ACS Omega (2017)

Design of Cocaethylene and Cocaine Conjugates to Produce Highly Selective Polyclonal Antibodies

מאת Gadjou, Caroline, Danger, Yannic, Sandouk, Pierre, Scherrmann, Jean-Michel, Blanchard, Dominique, Folléa, Gilles, Galons, Hervé
יצא לאור 2006

Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents

מאת Houzé, Sandrine, Hoang, Nha-Thu, Lozach, Olivier, Le Bras, Jacques, Meijer, Laurent, Galons, Hervé, Demange, Luc
הוצא לאור ב Molecules (2014)

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

מאת Barbezier, Nicolas, Chartier, Aymeric, Bidet, Yannick, Buttstedt, Anja, Voisset, Cécile, Galons, Hervé, Blondel, Marc, Schwarz, Elisabeth, Simonelig, Martine
יצא לאור 2011

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

מאת Bettayeb, Karima, Oumata, Nassima, Zhang, Yuanyuan, Luo, Wenjie, Bustos, Victor, Galons, Hervé, Greengard, Paul, Meijer, Laurent, Flajolet, Marc
יצא לאור 2012

F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

מאת Du, Chunyang, Li, Shuangshuang, Li, Yuan, Galons, Hervé, Guo, Na, Teng, Yuou, Zhang, Yongmin, Li, Mingyuan, Yu, Peng
הוצא לאור ב Drug Deliv (2020)

Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions

מאת Tribouillard-Tanvier, Déborah, Béringue, Vincent, Desban, Nathalie, Gug, Fabienne, Bach, Stéphane, Voisset, Cécile, Galons, Hervé, Laude, Hubert, Vilette, Didier, Blondel, Marc
יצא לאור 2008

The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

מאת Pang, Yanhong, Kurella, Sriram, Voisset, Cécile, Samanta, Dibyendu, Banerjee, Debapriya, Schabe, Ariane, Das Gupta, Chanchal, Galons, Hervé, Blondel, Marc, Sanyal, Suparna
יצא לאור 2013

Targeting low molecular weight cyclin E (LMW-E) in breast cancer

מאת Nanos-Webb, Angela, Jabbour, Natalie A., Multani, Asha S., Wingate, Hannah, Oumata, Nassima, Galons, Hervé, Joseph, Benoît, Meijer, Laurent, Hunt, Kelly K., Keyomarsi, Khandan
יצא לאור 2011

Aftins Increase Amyloid-β(42), Lower Amyloid-β(38), and Do Not Alter Amyloid-β(40) Extracellular Production in vitro: Toward a Chemical Model of Alzheimer’s Disease?

מאת Hochard, Arnaud, Oumata, Nassima, Bettayeb, Karima, Gloulou, Olfa, Fant, Xavier, Durieu, Emilie, Buron, Nelly, Porceddu, Mathieu, Borgne-Sanchez, Annie, Galons, Hervé, Flajolet, Marc, Meijer, Laurent
הוצא לאור ב J Alzheimers Dis (2013)

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

מאת Bettayeb, Karima, Baunbæk, Dianne, Delehouze, Claire, Loaëc, Nadège, Hole, Alison J., Baumli, Sonja, Endicott, Jane A., Douc-Rasy, Setha, Bénard, Jean, Oumata, Nassima, Galons, Hervé, Meijer, Laurent
יצא לאור 2010

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

מאת Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
יצא לאור 2012

Use of ATP analogs to inhibit HIV-1 transcription

מאת Narayanan, Aarthi, Sampey, Gavin, Van Duyne, Rachel, Guendel, Irene, Kehn-Hall, Kylene, Roman, Jessica, Currer, Robert, Galons, Hervé, Oumata, Nassima, Joseph, Benoît, Meijer, Laurent, Caputi, Massimo, Nekhai, Sergei, Kashanchi, Fatah
יצא לאור 2012

The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

מאת Oumata, Nassima, Nguyen, Phu hai, Beringue, Vincent, Soubigou, Flavie, Pang, Yanhong, Desban, Nathalie, Massacrier, Catherine, Morel, Yannis, Paturel, Carine, Contesse, Marie-Astrid, Bouaziz, Serge, Sanyal, Suparna, Galons, Hervé, Blondel, Marc, Voisset, Cécile
יצא לאור 2013

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

מאת Durieu, Emilie, Prina, Eric, Leclercq, Olivier, Oumata, Nassima, Gaboriaud-Kolar, Nicolas, Vougogiannopoulou, Konstantina, Aulner, Nathalie, Defontaine, Audrey, No, Joo Hwan, Ruchaud, Sandrine, Skaltsounis, Alexios-Leandros, Galons, Hervé, Späth, Gerald F., Meijer, Laurent, Rachidi, Najma
הוצא לאור ב Antimicrob Agents Chemother (2016)

CDK/CK1 inhibitors roscovitine and CR8 down-regulate amplified MYCN in neuroblastoma cells

מאת DELEHOUZE, Claire, GODL, Klaus, LOAEC, Nadège, BRUYERE, Céline, DESBAN, Nathalie, OUMATA, Nassima, GALONS, Hervé, ROUMELIOTIS, Theodoros I., GIANNOPOULOU, Eugenia G., GRENET, Jose, TWITCHELL, Devin, LAHTI, Jill, MOUCHET, Nicolas, GALIBERT, Marie-Dominique, GARBIS, Spiros D., MEIJER, Laurent
יצא לאור 2013

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

מאת Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Roux, Gwenaëlle Le, Fernandez-Varela, Paloma, Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
הוצא לאור ב Sci Rep (2020)