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Design of Cocaethylene and Cocaine Conjugates to Produce Highly Selective Polyclonal Antibodies

With the aim to obtain specific anti-cocaine antibodies directed against cocaine and active metabolites for use in immunotherapy, a series of six haptens were prepared, based on the structure of cocaine. The haptens differed by 3 positions of linkers: nitrogen, carboxyl group, and aromatic nucleus....

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Detalhes bibliográficos
Main Authors: Gadjou, Caroline, Danger, Yannic, Sandouk, Pierre, Scherrmann, Jean-Michel, Blanchard, Dominique, Folléa, Gilles, Galons, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Master Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614565/
https://ncbi.nlm.nih.gov/pubmed/23674968
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