FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects

Por Lagorce, David, Sperandio, Olivier, Galons, Hervé, Miteva, Maria A, Villoutreix, Bruno O
Publicado em 2008

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

Por Troadec, Samuel, Blairvacq, Mélina, Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Berthou, Christian
Publicado no J Biomed Sci (2015)

Antiprion Drugs as Chemical Tools to Uncover Mechanisms of Prion Propagation

Por Tribouillard, Déborah, Gug, Fabienne, Galons, Hervé, Bach, Stéphane, Saupe, Sven J, Blondel, Marc
Publicado em 2007

A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back...

Por El Hage, Krystel, Piquemal, Jean-Philip, Oumata, Nassima, Meijer, Laurent, Galons, Hervé, Gresh, Nohad
Publicado no ACS Omega (2017)

Design of Cocaethylene and Cocaine Conjugates to Produce Highly Selective Polyclonal Antibodies

Por Gadjou, Caroline, Danger, Yannic, Sandouk, Pierre, Scherrmann, Jean-Michel, Blanchard, Dominique, Folléa, Gilles, Galons, Hervé
Publicado em 2006

Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents

Por Houzé, Sandrine, Hoang, Nha-Thu, Lozach, Olivier, Le Bras, Jacques, Meijer, Laurent, Galons, Hervé, Demange, Luc
Publicado no Molecules (2014)

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

Por Barbezier, Nicolas, Chartier, Aymeric, Bidet, Yannick, Buttstedt, Anja, Voisset, Cécile, Galons, Hervé, Blondel, Marc, Schwarz, Elisabeth, Simonelig, Martine
Publicado em 2011

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

Por Bettayeb, Karima, Oumata, Nassima, Zhang, Yuanyuan, Luo, Wenjie, Bustos, Victor, Galons, Hervé, Greengard, Paul, Meijer, Laurent, Flajolet, Marc
Publicado em 2012

Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions

Por Tribouillard-Tanvier, Déborah, Béringue, Vincent, Desban, Nathalie, Gug, Fabienne, Bach, Stéphane, Voisset, Cécile, Galons, Hervé, Laude, Hubert, Vilette, Didier, Blondel, Marc
Publicado em 2008

The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Por Pang, Yanhong, Kurella, Sriram, Voisset, Cécile, Samanta, Dibyendu, Banerjee, Debapriya, Schabe, Ariane, Das Gupta, Chanchal, Galons, Hervé, Blondel, Marc, Sanyal, Suparna
Publicado em 2013

Targeting low molecular weight cyclin E (LMW-E) in breast cancer

Por Nanos-Webb, Angela, Jabbour, Natalie A., Multani, Asha S., Wingate, Hannah, Oumata, Nassima, Galons, Hervé, Joseph, Benoît, Meijer, Laurent, Hunt, Kelly K., Keyomarsi, Khandan
Publicado em 2011

Aftins Increase Amyloid-β(42), Lower Amyloid-β(38), and Do Not Alter Amyloid-β(40) Extracellular Production in vitro: Toward a Chemical Model of Alzheimer’s Disease?

Por Hochard, Arnaud, Oumata, Nassima, Bettayeb, Karima, Gloulou, Olfa, Fant, Xavier, Durieu, Emilie, Buron, Nelly, Porceddu, Mathieu, Borgne-Sanchez, Annie, Galons, Hervé, Flajolet, Marc, Meijer, Laurent
Publicado no J Alzheimers Dis (2013)

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

Por Bettayeb, Karima, Baunbæk, Dianne, Delehouze, Claire, Loaëc, Nadège, Hole, Alison J., Baumli, Sonja, Endicott, Jane A., Douc-Rasy, Setha, Bénard, Jean, Oumata, Nassima, Galons, Hervé, Meijer, Laurent
Publicado em 2010

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

Por Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Publicado em 2012

Use of ATP analogs to inhibit HIV-1 transcription

Por Narayanan, Aarthi, Sampey, Gavin, Van Duyne, Rachel, Guendel, Irene, Kehn-Hall, Kylene, Roman, Jessica, Currer, Robert, Galons, Hervé, Oumata, Nassima, Joseph, Benoît, Meijer, Laurent, Caputi, Massimo, Nekhai, Sergei, Kashanchi, Fatah
Publicado em 2012

The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

Por Oumata, Nassima, Nguyen, Phu hai, Beringue, Vincent, Soubigou, Flavie, Pang, Yanhong, Desban, Nathalie, Massacrier, Catherine, Morel, Yannis, Paturel, Carine, Contesse, Marie-Astrid, Bouaziz, Serge, Sanyal, Suparna, Galons, Hervé, Blondel, Marc, Voisset, Cécile
Publicado em 2013

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

Por Durieu, Emilie, Prina, Eric, Leclercq, Olivier, Oumata, Nassima, Gaboriaud-Kolar, Nicolas, Vougogiannopoulou, Konstantina, Aulner, Nathalie, Defontaine, Audrey, No, Joo Hwan, Ruchaud, Sandrine, Skaltsounis, Alexios-Leandros, Galons, Hervé, Späth, Gerald F., Meijer, Laurent, Rachidi, Najma
Publicado no Antimicrob Agents Chemother (2016)

CDK/CK1 inhibitors roscovitine and CR8 down-regulate amplified MYCN in neuroblastoma cells

Por DELEHOUZE, Claire, GODL, Klaus, LOAEC, Nadège, BRUYERE, Céline, DESBAN, Nathalie, OUMATA, Nassima, GALONS, Hervé, ROUMELIOTIS, Theodoros I., GIANNOPOULOU, Eugenia G., GRENET, Jose, TWITCHELL, Devin, LAHTI, Jill, MOUCHET, Nicolas, GALIBERT, Marie-Dominique, GARBIS, Spiros D., MEIJER, Laurent
Publicado em 2013

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Por Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Roux, Gwenaëlle Le, Fernandez-Varela, Paloma, Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
Publicado no Sci Rep (2020)

Author Correction: A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Por Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Le Roux, Gwenaëlle, Varela, Paloma F., Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
Publicado no Sci Rep (2020)