FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects

per Lagorce, David, Sperandio, Olivier, Galons, Hervé, Miteva, Maria A, Villoutreix, Bruno O
Publicat 2008

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

per Troadec, Samuel, Blairvacq, Mélina, Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Berthou, Christian
Publicat a J Biomed Sci (2015)

Antiprion Drugs as Chemical Tools to Uncover Mechanisms of Prion Propagation

per Tribouillard, Déborah, Gug, Fabienne, Galons, Hervé, Bach, Stéphane, Saupe, Sven J, Blondel, Marc
Publicat 2007

A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back...

per El Hage, Krystel, Piquemal, Jean-Philip, Oumata, Nassima, Meijer, Laurent, Galons, Hervé, Gresh, Nohad
Publicat a ACS Omega (2017)

Design of Cocaethylene and Cocaine Conjugates to Produce Highly Selective Polyclonal Antibodies

per Gadjou, Caroline, Danger, Yannic, Sandouk, Pierre, Scherrmann, Jean-Michel, Blanchard, Dominique, Folléa, Gilles, Galons, Hervé
Publicat 2006

Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents

per Houzé, Sandrine, Hoang, Nha-Thu, Lozach, Olivier, Le Bras, Jacques, Meijer, Laurent, Galons, Hervé, Demange, Luc
Publicat a Molecules (2014)

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

per Barbezier, Nicolas, Chartier, Aymeric, Bidet, Yannick, Buttstedt, Anja, Voisset, Cécile, Galons, Hervé, Blondel, Marc, Schwarz, Elisabeth, Simonelig, Martine
Publicat 2011

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action

per Bettayeb, Karima, Oumata, Nassima, Zhang, Yuanyuan, Luo, Wenjie, Bustos, Victor, Galons, Hervé, Greengard, Paul, Meijer, Laurent, Flajolet, Marc
Publicat 2012

F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

per Du, Chunyang, Li, Shuangshuang, Li, Yuan, Galons, Hervé, Guo, Na, Teng, Yuou, Zhang, Yongmin, Li, Mingyuan, Yu, Peng
Publicat a Drug Deliv (2020)

Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions

per Tribouillard-Tanvier, Déborah, Béringue, Vincent, Desban, Nathalie, Gug, Fabienne, Bach, Stéphane, Voisset, Cécile, Galons, Hervé, Laude, Hubert, Vilette, Didier, Blondel, Marc
Publicat 2008

The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

per Pang, Yanhong, Kurella, Sriram, Voisset, Cécile, Samanta, Dibyendu, Banerjee, Debapriya, Schabe, Ariane, Das Gupta, Chanchal, Galons, Hervé, Blondel, Marc, Sanyal, Suparna
Publicat 2013

Targeting low molecular weight cyclin E (LMW-E) in breast cancer

per Nanos-Webb, Angela, Jabbour, Natalie A., Multani, Asha S., Wingate, Hannah, Oumata, Nassima, Galons, Hervé, Joseph, Benoît, Meijer, Laurent, Hunt, Kelly K., Keyomarsi, Khandan
Publicat 2011

Aftins Increase Amyloid-β(42), Lower Amyloid-β(38), and Do Not Alter Amyloid-β(40) Extracellular Production in vitro: Toward a Chemical Model of Alzheimer’s Disease?

per Hochard, Arnaud, Oumata, Nassima, Bettayeb, Karima, Gloulou, Olfa, Fant, Xavier, Durieu, Emilie, Buron, Nelly, Porceddu, Mathieu, Borgne-Sanchez, Annie, Galons, Hervé, Flajolet, Marc, Meijer, Laurent
Publicat a J Alzheimers Dis (2013)

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

per Bettayeb, Karima, Baunbæk, Dianne, Delehouze, Claire, Loaëc, Nadège, Hole, Alison J., Baumli, Sonja, Endicott, Jane A., Douc-Rasy, Setha, Bénard, Jean, Oumata, Nassima, Galons, Hervé, Meijer, Laurent
Publicat 2010

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

per Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Publicat 2012

Use of ATP analogs to inhibit HIV-1 transcription

per Narayanan, Aarthi, Sampey, Gavin, Van Duyne, Rachel, Guendel, Irene, Kehn-Hall, Kylene, Roman, Jessica, Currer, Robert, Galons, Hervé, Oumata, Nassima, Joseph, Benoît, Meijer, Laurent, Caputi, Massimo, Nekhai, Sergei, Kashanchi, Fatah
Publicat 2012

The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

per Oumata, Nassima, Nguyen, Phu hai, Beringue, Vincent, Soubigou, Flavie, Pang, Yanhong, Desban, Nathalie, Massacrier, Catherine, Morel, Yannis, Paturel, Carine, Contesse, Marie-Astrid, Bouaziz, Serge, Sanyal, Suparna, Galons, Hervé, Blondel, Marc, Voisset, Cécile
Publicat 2013

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

per Durieu, Emilie, Prina, Eric, Leclercq, Olivier, Oumata, Nassima, Gaboriaud-Kolar, Nicolas, Vougogiannopoulou, Konstantina, Aulner, Nathalie, Defontaine, Audrey, No, Joo Hwan, Ruchaud, Sandrine, Skaltsounis, Alexios-Leandros, Galons, Hervé, Späth, Gerald F., Meijer, Laurent, Rachidi, Najma
Publicat a Antimicrob Agents Chemother (2016)

CDK/CK1 inhibitors roscovitine and CR8 down-regulate amplified MYCN in neuroblastoma cells

per DELEHOUZE, Claire, GODL, Klaus, LOAEC, Nadège, BRUYERE, Céline, DESBAN, Nathalie, OUMATA, Nassima, GALONS, Hervé, ROUMELIOTIS, Theodoros I., GIANNOPOULOU, Eugenia G., GRENET, Jose, TWITCHELL, Devin, LAHTI, Jill, MOUCHET, Nicolas, GALIBERT, Marie-Dominique, GARBIS, Spiros D., MEIJER, Laurent
Publicat 2013

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

per Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Roux, Gwenaëlle Le, Fernandez-Varela, Paloma, Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
Publicat a Sci Rep (2020)