Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?

nork Fullam, Elizabeth, Young, Robert J.
Argitaratua izan da RSC Med Chem (2020)

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

nork Otten, Lucienne, Fullam, Elizabeth, Gibson, Matthew I.
Argitaratua izan da Mol Biosyst (2016)

Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

nork Guy, Collette S., Gibson, Matthew I., Fullam, Elizabeth
Argitaratua izan da Chem Sci (2019)

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

nork Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Argitaratua izan da Open Biol (2016)

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

nork Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin
Argitaratua 2005

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

nork Fullam, Elizabeth, Pojer, Florence, Bergfors, Terese, Jones, T. Alwyn, Cole, Stewart T.
Argitaratua 2012

A GFP-strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatis

nork Radhakrishnan, Anjana, Furze, Christopher M., Ahangar, Mohd Syed, Fullam, Elizabeth
Argitaratua izan da RSC Adv (2018)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site

nork Abuhammad, Areej M., Lowe, Edward D., Fullam, Elizabeth, Noble, Martin, Garman, Elspeth F., Sim, Edith
Argitaratua izan da Protein Cell (2010)

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

nork Richards, Sarah-Jane, Isufi, Klea, Wilkins, Laura E., Lipecki, Julia, Fullam, Elizabeth, Gibson, Matthew I.
Argitaratua izan da Biomacromolecules (2017)

Structural Basis of Glycerophosphodiester Recognition by the Mycobacterium tuberculosis Substrate-Binding Protein UgpB

nork Fenn, Jonathan S., Nepravishta, Ridvan, Guy, Collette S., Harrison, James, Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Argitaratua izan da ACS Chem Biol (2019)

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

nork Karlikowska, Magdalena, Singh, Albel, Bhatt, Apoorva, Ott, Sascha, Bottrill, Andrew R., Besra, Gurdyal S., Fullam, Elizabeth
Argitaratua izan da Cell Surf (2021)

Exploration of Piperidinols as Potential Antitubercular Agents

nork Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela J., Morris, Garrett M., Finn, Paul W., Sim, Edith
Argitaratua izan da Molecules (2014)

Osmium–arene complexes with high potency towards Mycobacterium tuberculosis

nork Coverdale, James P C, Guy, Collette S, Bridgewater, Hannah E, Needham, Russell J, Fullam, Elizabeth, Sadler, Peter J
Argitaratua izan da Metallomics (2021)

Arylamine N-Acetyltransferases in Mycobacteria

nork Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin
Argitaratua 2008

Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)

nork Ahangar, Mohd Syed, Furze, Christopher M., Guy, Collette S., Cooper, Charlotte, Maskew, Kathryn S., Graham, Ben, Cameron, Alexander D., Fullam, Elizabeth
Argitaratua izan da J Biol Chem (2018)

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

nork Phillips, Daniel J., Harrison, James, Richards, Sarah-Jane, Mitchell, Daniel E., Tichauer, Esther, Hubbard, Alasdair T. M., Guy, Collette, Hands-Portman, Ian, Fullam, Elizabeth, Gibson, Matthew I.
Argitaratua izan da Biomacromolecules (2017)

Identification of the anti‐mycobacterial functional properties of piperidinol derivatives

nork Guy, Collette S, Tichauer, Esther, Kay, Gemma L, Phillips, Daniel J, Bailey, Trisha L, Harrison, James, Furze, Christopher M, Millard, Andrew D, Gibson, Matthew I, Pallen, Mark J, Fullam, Elizabeth
Argitaratua izan da Br J Pharmacol (2017)

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars

nork Westwood, Isaac M., Bhakta, Sanjib, Russell, Angela J., Fullam, Elizabeth, Anderton, Matthew C., Kawamura, Akane, Mulvaney, Andrew W., Vickers, Richard J., Bhowruth, Veemal, Besra, Gurdyal S., Lalvani, Ajit, Davies, Stephen G., Sim, Edith
Argitaratua izan da Protein Cell (2010)

Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter

nork Furze, Christopher M., Delso, Ignacio, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Argitaratua izan da J Biol Chem (2021)

Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages

nork Abuhammad, Areej, Fullam, Elizabeth, Lowe, Edward D., Staunton, David, Kawamura, Akane, Westwood, Isaac M., Bhakta, Sanjib, Garner, Alun Christopher, Wilson, David L., Seden, Peter T., Davies, Stephen G., Russell, Angela J., Garman, Elspeth F., Sim, Edith
Argitaratua 2012