Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?

per Fullam, Elizabeth, Young, Robert J.
Publicat a RSC Med Chem (2020)

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

per Otten, Lucienne, Fullam, Elizabeth, Gibson, Matthew I.
Publicat a Mol Biosyst (2016)

Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

per Guy, Collette S., Gibson, Matthew I., Fullam, Elizabeth
Publicat a Chem Sci (2019)

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

per Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Publicat a Open Biol (2016)

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

per Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin
Publicat 2005

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

per Fullam, Elizabeth, Pojer, Florence, Bergfors, Terese, Jones, T. Alwyn, Cole, Stewart T.
Publicat 2012

A GFP-strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatis

per Radhakrishnan, Anjana, Furze, Christopher M., Ahangar, Mohd Syed, Fullam, Elizabeth
Publicat a RSC Adv (2018)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site

per Abuhammad, Areej M., Lowe, Edward D., Fullam, Elizabeth, Noble, Martin, Garman, Elspeth F., Sim, Edith
Publicat a Protein Cell (2010)

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

per Richards, Sarah-Jane, Isufi, Klea, Wilkins, Laura E., Lipecki, Julia, Fullam, Elizabeth, Gibson, Matthew I.
Publicat a Biomacromolecules (2017)

Structural Basis of Glycerophosphodiester Recognition by the Mycobacterium tuberculosis Substrate-Binding Protein UgpB

per Fenn, Jonathan S., Nepravishta, Ridvan, Guy, Collette S., Harrison, James, Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Publicat a ACS Chem Biol (2019)

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

per Karlikowska, Magdalena, Singh, Albel, Bhatt, Apoorva, Ott, Sascha, Bottrill, Andrew R., Besra, Gurdyal S., Fullam, Elizabeth
Publicat a Cell Surf (2021)

Exploration of Piperidinols as Potential Antitubercular Agents

per Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela J., Morris, Garrett M., Finn, Paul W., Sim, Edith
Publicat a Molecules (2014)

Osmium–arene complexes with high potency towards Mycobacterium tuberculosis

per Coverdale, James P C, Guy, Collette S, Bridgewater, Hannah E, Needham, Russell J, Fullam, Elizabeth, Sadler, Peter J
Publicat a Metallomics (2021)

Arylamine N-Acetyltransferases in Mycobacteria

per Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin
Publicat 2008

Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)

per Ahangar, Mohd Syed, Furze, Christopher M., Guy, Collette S., Cooper, Charlotte, Maskew, Kathryn S., Graham, Ben, Cameron, Alexander D., Fullam, Elizabeth
Publicat a J Biol Chem (2018)

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

per Phillips, Daniel J., Harrison, James, Richards, Sarah-Jane, Mitchell, Daniel E., Tichauer, Esther, Hubbard, Alasdair T. M., Guy, Collette, Hands-Portman, Ian, Fullam, Elizabeth, Gibson, Matthew I.
Publicat a Biomacromolecules (2017)

Identification of the anti‐mycobacterial functional properties of piperidinol derivatives

per Guy, Collette S, Tichauer, Esther, Kay, Gemma L, Phillips, Daniel J, Bailey, Trisha L, Harrison, James, Furze, Christopher M, Millard, Andrew D, Gibson, Matthew I, Pallen, Mark J, Fullam, Elizabeth
Publicat a Br J Pharmacol (2017)

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars

per Westwood, Isaac M., Bhakta, Sanjib, Russell, Angela J., Fullam, Elizabeth, Anderton, Matthew C., Kawamura, Akane, Mulvaney, Andrew W., Vickers, Richard J., Bhowruth, Veemal, Besra, Gurdyal S., Lalvani, Ajit, Davies, Stephen G., Sim, Edith
Publicat a Protein Cell (2010)

Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter

per Furze, Christopher M., Delso, Ignacio, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Publicat a J Biol Chem (2021)

Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages

per Abuhammad, Areej, Fullam, Elizabeth, Lowe, Edward D., Staunton, David, Kawamura, Akane, Westwood, Isaac M., Bhakta, Sanjib, Garner, Alun Christopher, Wilson, David L., Seden, Peter T., Davies, Stephen G., Russell, Angela J., Garman, Elspeth F., Sim, Edith
Publicat 2012