Exposure to sub‐parts per million levels of vinyl chloride can increase the risk of developing liver injury

Por Fujiwara, Ryoichi
Publicado no Hepatol Commun (2018)

Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome

Por Fujiwara, Ryoichi, Itoh, Tomoo
Publicado em 2014

Expression pattern of human ATP-binding cassette transporters in skin

Por Takenaka, Saya, Itoh, Tomoo, Fujiwara, Ryoichi
Publicado em 2013

Expression of Human DNAJ (Heat Shock Protein-40) B3 in Humanized UDP-glucuronosyltransferase 1 Mice

Por Mitsugi, Ryo, Itoh, Tomoo, Fujiwara, Ryoichi
Publicado no Int J Mol Sci (2015)

Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases

Por Fujiwara, Ryoichi, Yokoi, Tsuyoshi, Nakajima, Miki
Publicado no Front Pharmacol (2016)

Species differences in drug glucuronidation: Humanized UDP-glucuronosyltransferase 1 mice and their application for predicting drug glucuronidation and drug-induced toxicity in hum...

Por Fujiwara, Ryoichi, Yoda, Emiko, Tukey, Robert H.
Publicado no Drug Metab Pharmacokinet (2017)

Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus

Por Fujiwara, Ryoichi, Nguyen, Nghia, Chen, Shujuan, Tukey, Robert H.
Publicado em 2010

Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia

Por FUJIWARA, RYOICHI, CHEN, SHUJUAN, KARIN, MICHAEL, TUKEY, ROBERT H.
Publicado em 2011

Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia

Por Shibuya, Ayako, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado em 2013

Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice

Por Kutsuno, Yuki, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado em 2014

Role of extrahepatic UDP-glucuronosyltransferase 1A1: advances in understanding breast milk-induced neonatal hyperbilirubinemia

Por Fujiwara, Ryoichi, Maruo, Yoshihiro, Chen, Shujuan, Tukey, Robert H.
Publicado no Toxicol Appl Pharmacol (2015)

Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain()

Por Sakamoto, Masaya, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado no Drug Metab Pharmacokinet (2015)

Prediction of drug-induced liver injury using keratinocytes

Por Hirashima, Rika, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado no J Appl Toxicol (2017)

Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders

Por Fujiwara, Ryoichi, Takenaka, Saya, Hashimoto, Mitsuhiro, Narawa, Tomoya, Itoh, Tomoo
Publicado em 2014

Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances

Por Li, Gen, Nakagome, Izumi, Hirono, Shuichi, Itoh, Tomoo, Fujiwara, Ryoichi
Publicado no Pharmacol Res Perspect (2015)

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia

Por Aoshima, Naoya, Fujie, Yoshiko, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado em 2014

Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes

Por Kutsuno, Yuki, Sumida, Kyohei, Itoh, Tomoo, Tukey, Robert H, Fujiwara, Ryoichi
Publicado em 2013

Severe neonatal hyperbilirubinemia in Crigler‐Najjar syndrome model mice can be reversed with zinc protoporphyrin

Por Fujiwara, Ryoichi, Mitsugi, Ryo, Uemura, Asuka, Itoh, Tomoo, Tukey, Robert H.
Publicado no Hepatol Commun (2017)

Vildagliptin and its metabolite M20.7 induce the expression of S100A8 and S100A9 in human hepatoma HepG2 and leukemia HL-60 cells

Por Asakura, Mitsutoshi, Karaki, Fumika, Fujii, Hideaki, Atsuda, Koichiro, Itoh, Tomoo, Fujiwara, Ryoichi
Publicado no Sci Rep (2016)

Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress

Por Yoda, Emiko, Paszek, Miles, Konopnicki, Camille, Fujiwara, Ryoichi, Chen, Shujuan, Tukey, Robert H.
Publicado no Sci Rep (2017)