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Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain()

UDP-glucuronosyltransferase (UGT) is a family of enzymes that catalyze the glucuronidation of various compounds, and thereby has an important role in metabolism and detoxification of a large number of xenobiotic and endogenous compounds. UGTs are present highly in the liver and small intestine, whil...

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Опубликовано в: :Drug Metab Pharmacokinet
Главные авторы: Sakamoto, Masaya, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752199/
https://ncbi.nlm.nih.gov/pubmed/26210671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dmpk.2015.04.004
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