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Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia

While breast milk has been known as a cause of neonatal hyperbilirubinemia, the underlying mechanism of breast milk-induced jaundice has not been clarified. Here, the impact of fatty acids on human UDP-glucuronosyltransferase (UGT) 1A1 – the sole enzyme that can metabolize bilirubin – were examined....

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Autori principali: Shibuya, Ayako, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793218/
https://ncbi.nlm.nih.gov/pubmed/24104695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02903
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