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Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances
Cordycepin, which is an analogue of a nucleoside adenosine, exhibits a wide variety of pharmacological activities including anticancer effects. In this study, ADA1- and ADA2-expressing HEK293 cells were established to determine the major ADA isoform responsible for the deamination of cordycepin. Whi...
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Publicado no: | Pharmacol Res Perspect |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448975/ https://ncbi.nlm.nih.gov/pubmed/26038697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.121 |
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