Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

Por Bremm, Anja, Freund, Stefan M.V., Komander, David
Publicado em 2010

Assembly, analysis and architecture of atypical ubiquitin chains

Por Hospenthal, Manuela K., Freund, Stefan M.V., Komander, David
Publicado em 2013

GpIbα Interacts Exclusively with Exosite II of Thrombin()

Por Lechtenberg, Bernhard C., Freund, Stefan M.V., Huntington, James A.
Publicado em 2014

The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis

Por Allen, Mark D., Freund, Stefan M.V., Zinzalla, Giovanna, Bycroft, Mark
Publicado no Structure (2015)

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90

Por Rüdiger, Stefan, Freund, Stefan M. V., Veprintsev, Dmitry B., Fersht, Alan R.
Publicado em 2002

Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core

Por Khoo, Kian Hoe, Joerger, Andreas C., Freund, Stefan M.V., Fersht, Alan R.
Publicado em 2009

High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1

Por Jacobsen, Julian O. B., Allen, Mark D., Freund, Stefan M. V., Bycroft, Mark
Publicado no Acta Crystallogr F Struct Biol Commun (2016)

NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation

Por Lechtenberg, Bernhard C., Johnson, Daniel J. D., Freund, Stefan M. V., Huntington, James A.
Publicado em 2010

Solution structure of the FCS zinc finger domain of the human polycomb group protein L(3)mbt-like 2

Por Lechtenberg, Bernhard C, Allen, Mark D, Rutherford, Trevor J, Freund, Stefan M V, Bycroft, Mark
Publicado em 2009

Molecular Basis for Modulation of the p53 Target Selectivity by KLF4

Por Brandt, Tobias, Townsley, Fiona M., Teufel, Daniel P., Freund, Stefan M. V., Veprintsev, Dmitry B.
Publicado em 2012

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

Por Gersch, Malte, Wagstaff, Jane L., Toms, Angela V., Graves, Bradford, Freund, Stefan M.V., Komander, David
Publicado no Mol Cell (2019)

Molecular basis of the interactions between the p73 N terminus and p300: Effects on transactivation and modulation by phosphorylation

Por Burge, Sarah, Teufel, Daniel P., Townsley, Fiona M., Freund, Stefan M. V., Bycroft, Mark, Fersht, Alan R.
Publicado em 2009

Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA

Por Sammak, Susan, Hamdani, Najoua, Gorrec, Fabrice, Allen, Mark D., Freund, Stefan M. V., Bycroft, Mark, Zinzalla, Giovanna
Publicado no Biochemistry (2019)

Hot-spot mutants of p53 core domain evince characteristic local structural changes

Por Wong, Kam-Bo, DeDecker, Brian S., Freund, Stefan M. V., Proctor, Mark R., Bycroft, Mark, Fersht, Alan R.
Publicado em 1999

Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution

Por Kazmirski, Steven L., Wong, Kam-Bo, Freund, Stefan M. V., Tan, Yee-Joo, Fersht, Alan R., Daggett, Valerie
Publicado em 2001

Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein

Por Alexander, Crispin G., Jürgens, Maike C., Shepherd, Dale A., Freund, Stefan M. V., Ashcroft, Alison E., Ferguson, Neil
Publicado em 2013

Solution structure of p53 core domain: Structural basis for its instability

Por Cañadillas, José Manuel Pérez, Tidow, Henning, Freund, Stefan M. V., Rutherford, Trevor J., Ang, Hwee Ching, Fersht, Alan R.
Publicado em 2006

Self-correcting mismatches during high-fidelity DNA replication

Por Fernandez-Leiro, Rafael, Conrad, Julian, Yang, Ji-Chun, Freund, Stefan M. V., Scheres, Sjors H. W., Lamers, Meindert H.
Publicado no Nat Struct Mol Biol (2017)

Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer

Por Natan, Eviatar, Baloglu, Cetin, Pagel, Kevin, Freund, Stefan M.V., Morgner, Nina, Robinson, Carol V., Fersht, Alan R., Joerger, Andreas C.
Publicado em 2011

Structure of PINK1 in complex with its substrate ubiquitin

Por Schubert, Alexander F., Gladkova, Christina, Pardon, Els, Wagstaff, Jane L., Freund, Stefan M.V., Steyaert, Jan, Maslen, Sarah L., Komander, David
Publicado no Nature (2017)