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GpIbα Interacts Exclusively with Exosite II of Thrombin()

Activation of platelets by the serine protease thrombin is a critical event in haemostasis. This process involves the binding of thrombin to glycoprotein Ibα (GpIbα) and cleavage of protease-activated receptors (PARs). The N-terminal extracellular domain of GpIbα contains an acidic peptide stretch t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lechtenberg, Bernhard C., Freund, Stefan M.V., Huntington, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919161/
https://ncbi.nlm.nih.gov/pubmed/24316004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.11.027
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