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GpIbα Interacts Exclusively with Exosite II of Thrombin()
Activation of platelets by the serine protease thrombin is a critical event in haemostasis. This process involves the binding of thrombin to glycoprotein Ibα (GpIbα) and cleavage of protease-activated receptors (PARs). The N-terminal extracellular domain of GpIbα contains an acidic peptide stretch t...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919161/ https://ncbi.nlm.nih.gov/pubmed/24316004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.11.027 |
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