Binding of human alpha-thrombin to platelet GpIb: energetics and functional effects.

Thrombin interaction with platelet glycocalicin (GC), the 140 kDa extracytoplasmic fragment of the membrane glycoprotein Ib, was investigated by using a solid-phase assay. Thrombin bound to GC-coated polystyrene wells was detected by measuring the hydrolysis of a chromogenic substrate. The monoclona...

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Hlavní autoři: de Cristofaro, R, de Candia, E, Croce, G, Morosetti, R, Landolfi, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219523/
https://ncbi.nlm.nih.gov/pubmed/9620865
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