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Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA
[Image: see text] The c-MYC transcription factor is a master regulator of cell growth and proliferation and is an established target for cancer therapy. This basic helix–loop–helix Zip protein forms a heterodimer with its obligatory partner MAX, which binds to DNA via the basic region. Considerable...
Gorde:
| Argitaratua izan da: | Biochemistry |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American
Chemical Society
2019
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6791285/ https://ncbi.nlm.nih.gov/pubmed/31260268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00296 |
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