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Molecular basis of the interactions between the p73 N terminus and p300: Effects on transactivation and modulation by phosphorylation

The transcription factor p73 belongs to the p53 family of proteins and can transactivate a number of target genes in common with p53. Here, we characterized the interaction of the p73 N terminus with four domains of the transcriptional coactivator p300 and with the negative regulator Mdm2 by using b...

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Detalhes bibliográficos
Main Authors: Burge, Sarah, Teufel, Daniel P., Townsley, Fiona M., Freund, Stefan M. V., Bycroft, Mark, Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651247/
https://ncbi.nlm.nih.gov/pubmed/19218448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900383106
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