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Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

The evolutionarily related deubiquitinating enzymes (DUBs) USP25 and USP28 comprise an identical overall domain architecture but are functionally non-redundant: USP28 stabilizes c-MYC and other nuclear proteins, and USP25 regulates inflammatory TRAF signaling. We here compare molecular features of U...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Gersch, Malte, Wagstaff, Jane L., Toms, Angela V., Graves, Bradford, Freund, Stefan M.V., Komander, David
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509359/
https://ncbi.nlm.nih.gov/pubmed/30926242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.030
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