Caricamento...
Mechanism and regulation of the Lys6-selective deubiquitinase USP30
Damaged mitochondria undergo a specialised form of autophagy termed mitophagy, which is initiated by the ubiquitin kinase PINK1 and the E3 ligase Parkin. Ubiquitin-specific protease USP30 antagonises Parkin-mediated ubiquitination events on mitochondria and is a key negative regulator of mitophagy....
Salvato in:
| Pubblicato in: | Nat Struct Mol Biol |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757785/ https://ncbi.nlm.nih.gov/pubmed/28945249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3475 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|