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Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne
The post-translational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology. Eight distinct chain linkage types in polyubiquitin co-exist and are independently regulated in cells. This ‘ubiquitin code’ determines the fate of the modified protein1. Deubiquitinat...
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| Publicado en: | Nature |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5295632/ https://ncbi.nlm.nih.gov/pubmed/27732584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19836 |
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