The quest for genetic risk factors for Crohn's disease in the post-GWAS era

Por Fransen, Karin, Mitrovic, Mitja, van Diemen, Cleo C, Weersma, Rinse K
Publicado em 2011

Cytokine Profile in a Cohort of Healthy Blood Donors Carrying Polymorphisms in Genes Encoding the NLRP3 Inflammasome

Por Sahdo, Berolla, Fransén, Karin, Asfaw Idosa, Berhane, Eriksson, Per, Söderquist, Bo, Kelly, Anne, Särndahl, Eva
Publicado em 2013

Q705K variant in NLRP3 gene confers protection against myocardial infarction in female individuals

Por VARGHESE, GEENA PARAMEL, FRANSÉN, KARIN, HURTIG-WENNLÖF, ANITA, BENGTSSON, TORBJÖRN, JANSSON, JAN-HÅKAN, SIRSJÖ, ALLAN
Publicado em 2013

Polymorphism in the Retinoic Acid Metabolizing Enzyme CYP26B1 and the Development of Crohn’s Disease

Por Fransén, Karin, Franzén, Petra, Magnuson, Anders, Elmabsout, Ali Ateia, Nyhlin, Nils, Wickbom, Anna, Curman, Bengt, Törkvist, Leif, D’Amato, Mauro, Bohr, Johan, Tysk, Curt, Sirsjö, Allan, Halfvarson, Jonas
Publicado em 2013

Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci

Por Fransen, Karin, Mitrovic, Mitja, van Diemen, Cleo C., B.K., Thelma, Sood, Ajit, Franke, Andre, Schreiber, Stefan, Midha, Vandana, Juyal, Garima, Potocnik, Uros, Fu, Jingyuan, Nolte, Ilja, Weersma, Rinse K.
Publicado em 2012

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

Por Paramel Varghese, Geena, Folkersen, Lasse, Strawbridge, Rona J., Halvorsen, Bente, Yndestad, Arne, Ranheim, Trine, Krohg‐Sørensen, Kirsten, Skjelland, Mona, Espevik, Terje, Aukrust, Pål, Lengquist, Mariette, Hedin, Ulf, Jansson, Jan‐Håkan, Fransén, Karin, Hansson, Göran K., Eriksson, Per, Sirsjö, Allan
Publicado no J Am Heart Assoc (2016)

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Por Smeekens, Sanne P., Ng, Aylwin, Kumar, Vinod, Johnson, Melissa D., Plantinga, Theo S., van Diemen, Cleo, Arts, Peer, Verwiel, Eugéne T.P., Gresnigt, Mark S., Fransen, Karin, van Sommeren, Suzanne, Oosting, Marije, Cheng, Shih-Chin, Joosten, Leo A.B., Hoischen, Alexander, Kullberg, Bart-Jan, Scott, William K., Perfect, John R., van der Meer, Jos W.M., Wijmenga, Cisca, Netea, Mihai G., Xavier, Ramnik J.
Publicado em 2013

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

Por Franke, Lude, el Bannoudi, Hanane, Jansen, Diahann T S L, Kok, Klaas, Trynka, Gosia, Diogo, Dorothee, Swertz, Morris, Fransen, Karin, Knevel, Rachel, Gutierrez-Achury, Javier, Ärlestig, Lisbeth, Greenberg, Jeffrey D, Kremer, Joel, Pappas, Dimitrios A, Kanterakis, Alexandros, Weersma, Rinse K, van der Helm-van Mil, Annette H M, Guryev, Viktor, Rantapää-Dahlqvist, Solbritt, Gregersen, Peter K, Plenge, Robert M, Wijmenga, Cisca, Huizinga, Tom W-J, Ioan-Facsinay, Andreea, Toes, Rene E M, Zhernakova, Alexandra
Publicado no Eur J Hum Genet (2016)

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

Por Trynka, Gosia, Hunt, Karen A, Bockett, Nicholas A, Romanos, Jihane, Mistry, Vanisha, Szperl, Agata, Bakker, Sjoerd F, Bardella, Maria Teresa, Bhaw-Rosun, Leena, Castillejo, Gemma, de la Concha, Emilio G., de Almeida, Rodrigo Coutinho, Dias, Kerith-Rae M, van Diemen, Cleo C., Dubois, Patrick CA, Duerr, Richard H., Edkins, Sarah, Franke, Lude, Fransen, Karin, Gutierrez, Javier, Heap, Graham AR, Hrdlickova, Barbara, Hunt, Sarah, Izurieta, Leticia Plaza, Izzo, Valentina, Joosten, Leo AB, Langford, Cordelia, Mazzilli, Maria Cristina, Mein, Charles A, Midah, Vandana, Mitrovic, Mitja, Mora, Barbara, Morelli, Marinita, Nutland, Sarah, Núñez, Concepción, Onengut-Gumuscu, Suna, Pearce, Kerra, Platteel, Mathieu, Polanco, Isabel, Potter, Simon, Ribes-Koninckx, Carmen, Ricaño-Ponce, Isis, Rich, Stephen S., Rybak, Anna, Santiago, José Luis, Senapati, Sabyasachi, Sood, Ajit, Szajewska, Hania, Troncone, Riccardo, Varadé, Jezabel, Wallace, Chris, Wolters, Victorien M, Zhernakova, Alexandra, Thelma, B.K., Cukrowska, Bozena, Urcelay, Elena, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Barrett, Jeffrey C, Plagnol, Vincent, Deloukas, Panos, Wijmenga, Cisca, van Heel, David A
Publicado em 2011

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Por Hunt, Karen A, Smyth, Deborah J, Balschun, Tobias, Ban, Maria, Mistry, Vanisha, Ahmed, Tariq, Anand, Vidya, Barrett, Jeffrey C, Bhaw-Rosun, Leena, Bockett, Nicholas A, Brand, Oliver J, Brouwer, Elisabeth, Concannon, Patrick, Cooper, Jason D, Dias, Kerith-Rae M, van Diemen, Cleo C, Dubois, Patrick C, Edkins, Sarah, Fölster-Holst, Regina, Fransen, Karin, Glass, David N., Heap, Graham AR, Hofmann, Sylvia, Huizinga, Tom WJ, Hunt, Sarah, Langford, Cordelia, Lee, James, Mansfield, John, Marrosu, Maria Giovanna, Mathew, Christopher G, Mein, Charles A, Müller-Quernheim, Joachim, Nutland, Sarah, Onengut-Gumuscu, Suna, Ouwehand, Willem, Pearce, Kerra, Prescott, Natalie, Posthumus, Marcel D, Potter, Simon, Rosati, Giulio, Sambrook, Jennifer, Satsangi, Jack, Schreiber, Stefan, Shtir, Corina, Simmonds, Matthew J, Sudman, Marc, Thompson, Susan D, Toes, Rene, Trynka, Gosia, Vyse, Timothy J, Walker, Neil M, Weidinger, Stephan, Zhernakova, Alexandra, Zoledziewska, Magdalena, Weersma, Rinse K, Gough, Stephen CL, Sawcer, Stephen, Wijmenga, Cisca, Parkes, Miles, Cucca, Francesco, Franke, Andre, Deloukas, Panos, Rich, Stephen S., Todd, John A, van Heel, David A
Publicado em 2011

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Por Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, McGovern, Dermot P, Hui, Ken Y, Lee, James C, Schumm, L Philip, Sharma, Yashoda, Anderson, Carl A, Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N, Andersen, Vibeke, Andrews, Jane M, Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A, Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Devaney, Kathy L, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R, Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H, Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R, Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y, Potocnik, Uros, Prescott, Natalie J, Regueiro, Miguel, Rotter, Jerome I, Russell, Richard K, Sanderson, Jeremy D, Sans, Miquel, Satsangi, Jack, Schreiber, Stefan, Simms, Lisa A, Sventoraityte, Jurgita, Targan, Stephan R, Taylor, Kent D, Tremelling, Mark, Verspaget, Hein W, De Vos, Martine, Wijmenga, Cisca, Wilson, David C, Winkelmann, Juliane, Xavier, Ramnik J, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K, Zhao, Hongyu, Silverberg, Mark S, Annese, Vito, Hakonarson, Hakon, Brant, Steven R, Radford-Smith, Graham, Mathew, Christopher G, Rioux, John D, Schadt, Eric E, Daly, Mark J, Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C, Cho, Judy H
Publicado em 2012