Polymorphism in the Retinoic Acid Metabolizing Enzyme CYP26B1 and the Development of Crohn’s Disease

Several studies suggest that Vitamin A may be involved in the pathogenesis of inflammatory bowel disease (IBD), but the mechanism is still unknown. Cytochrome P450 26 B1 (CYP26B1) is involved in the degradation of retinoic acid and the polymorphism rs2241057 has an elevated catabolic function of ret...

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Bibliografiska uppgifter
Huvudupphovsmän: Fransén, Karin, Franzén, Petra, Magnuson, Anders, Elmabsout, Ali Ateia, Nyhlin, Nils, Wickbom, Anna, Curman, Bengt, Törkvist, Leif, D’Amato, Mauro, Bohr, Johan, Tysk, Curt, Sirsjö, Allan, Halfvarson, Jonas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747106/
https://ncbi.nlm.nih.gov/pubmed/23977348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072739
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