Polymorphism in the Retinoic Acid Metabolizing Enzyme CYP26B1 and the Development of Crohn’s Disease

Several studies suggest that Vitamin A may be involved in the pathogenesis of inflammatory bowel disease (IBD), but the mechanism is still unknown. Cytochrome P450 26 B1 (CYP26B1) is involved in the degradation of retinoic acid and the polymorphism rs2241057 has an elevated catabolic function of ret...

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Main Authors: Fransén, Karin, Franzén, Petra, Magnuson, Anders, Elmabsout, Ali Ateia, Nyhlin, Nils, Wickbom, Anna, Curman, Bengt, Törkvist, Leif, D’Amato, Mauro, Bohr, Johan, Tysk, Curt, Sirsjö, Allan, Halfvarson, Jonas
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747106/
https://ncbi.nlm.nih.gov/pubmed/23977348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072739
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