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Polymorphism in the Retinoic Acid Metabolizing Enzyme CYP26B1 and the Development of Crohn’s Disease

Several studies suggest that Vitamin A may be involved in the pathogenesis of inflammatory bowel disease (IBD), but the mechanism is still unknown. Cytochrome P450 26 B1 (CYP26B1) is involved in the degradation of retinoic acid and the polymorphism rs2241057 has an elevated catabolic function of ret...

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Bibliografski detalji
Glavni autori: Fransén, Karin, Franzén, Petra, Magnuson, Anders, Elmabsout, Ali Ateia, Nyhlin, Nils, Wickbom, Anna, Curman, Bengt, Törkvist, Leif, D’Amato, Mauro, Bohr, Johan, Tysk, Curt, Sirsjö, Allan, Halfvarson, Jonas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747106/
https://ncbi.nlm.nih.gov/pubmed/23977348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072739
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