Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci

BACKGROUND: Genome-wide association studies of two main forms of inflammatory bowel diseases (IBD), Crohn’s disease (CD) and ulcerative colitis (UC), have identified 99 susceptibility loci, but these explain only ∼23% of the genetic risk. Part of the ‘hidden heritability’ could be in transmissible g...

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Detalhes bibliográficos
Main Authors: Fransen, Karin, Mitrovic, Mitja, van Diemen, Cleo C., B.K., Thelma, Sood, Ajit, Franke, Andre, Schreiber, Stefan, Midha, Vandana, Juyal, Garima, Potocnik, Uros, Fu, Jingyuan, Nolte, Ilja, Weersma, Rinse K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459955/
https://ncbi.nlm.nih.gov/pubmed/23028907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045287
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