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Cytokine Profile in a Cohort of Healthy Blood Donors Carrying Polymorphisms in Genes Encoding the NLRP3 Inflammasome

BACKGROUND: The NLRP3 inflammasome has been recognized as one of the key components of the innate immunity by sensing a diversity of insults. Inflammasome activation results in the maturation of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. Increased production of IL-1β is found in p...

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Detalhes bibliográficos
Main Authors: Sahdo, Berolla, Fransén, Karin, Asfaw Idosa, Berhane, Eriksson, Per, Söderquist, Bo, Kelly, Anne, Särndahl, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789710/
https://ncbi.nlm.nih.gov/pubmed/24098386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075457
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