Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity

Por Fischer, Nicholas W., Prodeus, Aaron, Gariépy, Jean
Publicado no JCI Insight (2018)

p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis

Por Fischer, Nicholas W., Prodeus, Aaron, Malkin, David, Gariépy, Jean
Publicado no Cell Cycle (2016)

Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome

Por Fischer, Nicholas W, Prodeus, Aaron, Tran, James, Malkin, David, Gariépy, Jean
Publicado no J Natl Cancer Inst (2018)

Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers

Por Prodeus, Aaron, Abdul-Wahid, Aws, Fischer, Nicholas W., Huang, Eric H-B, Cydzik, Marzena, Gariépy, Jean
Publicado no Mol Ther Nucleic Acids (2015)

A Synthetic Cross-Species CD200R1 Agonist Suppresses Inflammatory Immune Responses In Vivo

Por Prodeus, Aaron, Sparkes, Amanda, Fischer, Nicholas W., Cydzik, Marzena, Huang, Eric, Khatri, Ismat, Young, Ashley, Woo, Lindsay, Chow, Chung Wai, Gorczynski, Reginald, Gariépy, Jean
Publicado no Mol Ther Nucleic Acids (2018)

Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cel...

Por Abdul-Wahid, Aws, Cydzik, Marzena, Fischer, Nicholas W., Prodeus, Aaron, Shively, John E, Martel, Anne, Alminawi, Samira, Ghorab, Zeina, Berinstein, Neil L., Gariépy, Jean
Publicado no Int J Cancer (2018)

VISTA.COMP — an engineered checkpoint receptor agonist that potently suppresses T cell–mediated immune responses

Por Prodeus, Aaron, Abdul-Wahid, Aws, Sparkes, Amanda, Fischer, Nicholas W., Cydzik, Marzena, Chiang, Nicholas, Alwash, Mays, Ferzoco, Alessandra, Vacaresse, Nathalie, Julius, Michael, Gorczysnki, Reginald M., Gariépy, Jean
Publicado no JCI Insight (2017)

Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network

Por Samuel, Nardin, Wilson, Gavin, Said, Badr Id, Pan, Anna, Deblois, Genevieve, Fischer, Nicholas W., Alexandrova, Roumiana, Casallo, Guillermo, Paton, Tara, Lupien, Mathieu, Gariepy, Jean, Merico, Daniele, Hudson, Thomas J., Malkin, David
Publicado no Oncotarget (2016)

TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy

Por Graziano, Francesco, Fischer, Nicholas W., Bagaloni, Irene, Di Bartolomeo, Maria, Lonardi, Sara, Vincenzi, Bruno, Perrone, Giuseppe, Fornaro, Lorenzo, Ongaro, Elena, Aprile, Giuseppe, Bisonni, Renato, Prisciandaro, Michele, Malkin, David, Gariépy, Jean, Fassan, Matteo, Loupakis, Fotios, Sarti, Donatella, Del Prete, Michela, Catalano, Vincenzo, Alessandroni, Paolo, Magnani, Mauro, Ruzzo, Annamaria
Publicado no Cancers (Basel) (2020)