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VISTA.COMP — an engineered checkpoint receptor agonist that potently suppresses T cell–mediated immune responses
V-domain immunoglobulin suppressor of T cell activation (VISTA) is a recently discovered immune checkpoint ligand that functions to suppress T cell activity. The therapeutic potential of activating this immune checkpoint pathway to reduce inflammatory responses remains untapped, largely due to the i...
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| Publicado no: | JCI Insight |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621893/ https://ncbi.nlm.nih.gov/pubmed/28931757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94308 |
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