Agonistic CD200R1 DNA Aptamers Are Potent Immunosuppressants That Prolong Allogeneic Skin Graft Survival

CD200R1 expressed on the surface of myeloid and lymphoid cells delivers immune inhibitory signals to modulate inflammation when engaged with its ligand CD200. Signalling through CD200/CD200R1 has been implicated in a number of immune-related diseases including allergy, infection, cancer and transpla...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Prodeus, Aaron, Cydzik, Marzena, Abdul-Wahid, Aws, Huang, Eric, Khatri, Ismat, Gorczynski, Reginald, Gariépy, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221601/
https://ncbi.nlm.nih.gov/pubmed/25158092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.41
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