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Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity
BACKGROUND. There is currently no clinical distinction between different TP53 mutations, despite increasing evidence that not all mutations have equally deleterious effects on the activity of the encoded tumor suppressor protein p53. The objective of this study was to determine whether these biologi...
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| Опубликовано в: : | JCI Insight |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129128/ https://ncbi.nlm.nih.gov/pubmed/30089713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121364 |
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