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Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma
Despite the propensity for gastric and esophageal adenocarcinomas to select for recurrent missense mutations in TP53, the precise functional consequence of these mutations remains unclear. Here we report that endogenous mRNA and protein levels of mutant p53 were elevated in cell lines and patients w...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | JCI Insight |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693823/ https://ncbi.nlm.nih.gov/pubmed/31391338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128439 |
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