Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NF-κB Signalling

Por Amyot, Julie, Semache, Meriem, Ferdaoussi, Mourad, Fontés, Ghislaine, Poitout, Vincent
Publicado em 2012

ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis

Por Abderrahmani, Amar, Cheviet, Séverine, Ferdaoussi, Mourad, Coppola, Thierry, Waeber, Gérard, Regazzi, Romano
Publicado em 2006

Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1

Por Kebede, Melkam, Ferdaoussi, Mourad, Mancini, Arturo, Alquier, Thierry, Kulkarni, Rohit N., Walker, Michael D., Poitout, Vincent
Publicado em 2012

Binding of Activating Transcription Factor 6 to the A5/Core of the Rat Insulin II Gene Promoter does not Mediate its Transcriptional Repression

Por Amyot, Julie, Benterki, Isma, Fontés, Ghislaine, Hagman, Derek K., Ferdaoussi, Mourad, Teodoro, Tracy, Volchuk, Allen, Joly, Érik, Poitout, Vincent
Publicado em 2011

SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets

Por Hajmrle, Catherine, Ferdaoussi, Mourad, Plummer, Gregory, Spigelman, Aliya F., Lai, Krista, Manning Fox, Jocelyn E., MacDonald, Patrick E.
Publicado em 2014

Interleukin-1 signaling contributes to acute islet compensation

Por Hajmrle, Catherine, Smith, Nancy, Spigelman, Aliya F., Dai, Xiaoqing, Senior, Laura, Bautista, Austin, Ferdaoussi, Mourad, MacDonald, Patrick E.
Publicado no JCI Insight (2016)

SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells

Por Ferdaoussi, Mourad, Fu, Jianyang, Dai, Xiaoqing, Manning Fox, Jocelyn E., Suzuki, Kunimasa, Smith, Nancy, Plummer, Gregory, MacDonald, Patrick E.
Publicado no Sci Rep (2017)

Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity

Por Brajkovic, Saška, Ferdaoussi, Mourad, Pawlowski, Valérie, Ezanno, Hélène, Plaisance, Valérie, Zmuda, Erik, Hai, Tsonwin, Annicotte, Jean-Sébastien, Waeber, Gérard, Abderrahmani, Amar
Publicado no J Diabetes Res (2016)

PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets

Por Kolic, Jelena, Manning Fox, Jocelyn E., Chepurny, Oleg G., Spigelman, Aliya F., Ferdaoussi, Mourad, Schwede, Frank, Holz, George G., MacDonald, Patrick E.
Publicado no Mol Metab (2016)

Adenylosuccinate is an insulin secretagogue derived from glucose-induced purine metabolism

Por Gooding, Jessica R., Jensen, Mette V., Dai, Xiaoqing, Wenner, Brett R., Lu, Danhong, Arumugam, Ramamani, Ferdaoussi, Mourad, MacDonald, Patrick E., Newgard, Christopher B.
Publicado no Cell Rep (2015)

A unique set of SH3–SH3 interactions controls IB1 homodimerization

Por Kristensen, Ole, Guenat, Sylvie, Dar, Imran, Allaman-Pillet, Nathalie, Abderrahmani, Amar, Ferdaoussi, Mourad, Roduit, Raphaël, Maurer, Fabienne, Beckmann, Jacques S, Kastrup, Jette S, Gajhede, Michael, Bonny, Christophe
Publicado em 2006

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

Por Ferdaoussi, Mourad, Dai, Xiaoqing, Jensen, Mette V., Wang, Runsheng, Peterson, Brett S., Huang, Chao, Ilkayeva, Olga, Smith, Nancy, Miller, Nathanael, Hajmrle, Catherine, Spigelman, Aliya F., Wright, Robert C., Plummer, Gregory, Suzuki, Kunimasa, Mackay, James P., van de Bunt, Martijn, Gloyn, Anna L., Ryan, Terence E., Norquay, Lisa D., Brosnan, M. Julia, Trimmer, Jeff K., Rolph, Timothy P., Kibbey, Richard G., Manning Fox, Jocelyn E., Colmers, William F., Shirihai, Orian S., Neufer, P. Darrell, Yeh, Edward T.H., Newgard, Christopher B., MacDonald, Patrick E.
Publicado no J Clin Invest (2015)