A protein-domain microarray identifies novel protein-protein interactions.

Por Espejo, Alexsandra, Côté, Jocelyn, Bednarek, Andrzej, Richard, Stephane, Bedford, Mark T
Publicado em 2002

Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2

Por Hadjikyriacou, Andrea, Yang, Yanzhong, Espejo, Alexsandra, Bedford, Mark T., Clarke, Steven G.
Publicado no J Biol Chem (2015)

TDRD3 is an Effector Molecule for Arginine Methylated Histone Marks

Por Yang, Yanzhong, Lu, Yue, Espejo, Alexsandra, Wu, Jiacai, Xu, Wei, Liang, Shoudan, Bedford, Mark T.
Publicado em 2010

Zdhhc13-dependent Drp1 S-palmitoylation impacts brain bioenergetics, anxiety, coordination and motor skills

Por Napoli, Eleonora, Song, Gyu, Liu, Siming, Espejo, Alexsandra, Perez, Carlos J., Benavides, Fernando, Giulivi, Cecilia
Publicado no Sci Rep (2017)

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Por Kim, Jeesun, Daniel, Jeremy, Espejo, Alexsandra, Lake, Aimee, Krishna, Murli, Xia, Li, Zhang, Yi, Bedford, Mark T
Publicado em 2006

A homogeneous method for investigation of methylation-dependent protein–protein interactions in epigenetics

Por Quinn, Amy M., Bedford, Mark T., Espejo, Alexsandra, Spannhoff, Astrid, Austin, Christopher P., Oppermann, Udo, Simeonov, Anton
Publicado em 2010

Phosphorylation-dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex

Por Kapoor, Prabodh, Bao, Yunhe, Xiao, Jing, Espejo, Alexsandra, Yang, Lin, Bedford, Mark T., Peng, Guang, Shen, Xuetong
Publicado no Mol Cell (2015)

DDRE-31. EVALUATION OF HIGHLY POTENT AND SELECTIVE SINGLE-MOLECULE DUAL EGFR/PI3K INHIBITORS IN ADULT AND PEDIATRIC HIGH-GRADE GLIOMA

Por Gangadharan, Achintyan, Sun, Yusha, Bailey, Cavan, Carter, Trever, Espejo, Alexsandra, Whitehead, Christopher, Leopold, Judith, Chandra, Joya
Publicado no Neuro Oncol (2020)

Interaction of Proliferation Cell Nuclear Antigen (PCNA) with c-Abl in Cell Proliferation and Response to DNA Damages in Breast Cancer

Por Zhao, Huajun, Ho, Po-Chun, Lo, Yuan-Hung, Espejo, Alexsandra, Bedford, Mark T., Hung, Mien-Chie, Wang, Shao-Chun
Publicado em 2012

EXTH-75. IN VITRO AND IN VIVO EFFICACY OF COMBINATORIAL INHIBITION OF LSD1 AND HDACS IN PATIENT DERIVED GLIOBLASTOMA STEM CELL MODELS

Por Gangadharan, Achintyan, Grasse, Leslie, Espejo, Alexsandra, Ezhilarasan, Ravesanker, Collier, Tiara, Henry, Verlene, Gumin, Joy, Sulman, Erik, Lang, Frederick, Chandra, Joya
Publicado no Neuro Oncol (2020)

Methyllysine Reader Plant Homeodomain (PHD) Finger Protein 20-like 1 (PHF20L1) Antagonizes DNA (Cytosine-5) Methyltransferase 1 (DNMT1) Proteasomal Degradation

Por Estève, Pierre-Olivier, Terragni, Jolyon, Deepti, Kanneganti, Chin, Hang Gyeong, Dai, Nan, Espejo, Alexsandra, Corrêa, Ivan R., Bedford, Mark T., Pradhan, Sriharsa
Publicado em 2014

PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch

Por Espejo, Alexsandra B., Gao, Guozhen, Black, Karynne, Gayatri, Sitaram, Veland, Nicolas, Kim, Jeesun, Chen, Taiping, Sudol, Marius, Walker, Cheryl, Bedford, Mark T.
Publicado no J Biol Chem (2017)

Crystal Structure of Three Tandem FF Domains of Transcription Elongation Regulator CA150

Por Lu, Ming, Yang, Jun, Ren, Zhiyong, Sabui, Subir, Espejo, Alexsandra, Bedford, Mark T., Jacobson, Raymond H., Jeruzalmi, David, McMurray, John S., Chen, Xiaomin
Publicado em 2009

Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14–3–3 proteins in vitro

Por Tetenborg, Stephan, Wang, Helen Y., Nemitz, Lena, Depping, Anne, Espejo, Alexsandra B., Aseervatham, Jaya, Bedford, Mark T., Janssen-Bienhold, Ulrike, O’Brien, John, Dedek, Karin
Publicado no Sci Rep (2020)

Epigenome Microarray Platform for Proteome-Wide Dissection of Chromatin-Signaling Networks

Por Bua, Dennis J., Kuo, Alex J., Cheung, Peggie, Liu, Chih Long, Migliori, Valentina, Espejo, Alexsandra, Casadio, Fabio, Bassi, Christian, Amati, Bruno, Bedford, Mark T., Guccione, Ernesto, Gozani, Or
Publicado em 2009

Methylation by Set9 modulates FoxO3 stability and transcriptional activity

Por Calnan, Daniel R., Webb, Ashley E., White, Jamie L., Stowe, Timothy R., Goswami, Tapasree, Shi, Xiaobing, Espejo, Alexsandra, Bedford, Mark T., Gozani, Or, Gygi, Steven P., Brunet, Anne
Publicado em 2012

MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a

Por Chang, Yanqi, Sun, Lidong, Kokura, Kenji, Horton, John R., Fukuda, Mikiko, Espejo, Alexsandra, Izumi, Victoria, Koomen, John M., Bedford, Mark T., Zhang, Xing, Shinkai, Yoichi, Fang, Jia, Cheng, Xiaodong
Publicado em 2011

Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes

Por Zhu, Feng, Dollé, Martijn E.T., Berton, Thomas R., Kuiper, Raoul V., Capps, Carrie, Espejo, Alexsandra, McArthur, Mark J., Bedford, Mark T., van Steeg, Harry, de Vries, Annemieke, Johnson, David G.
Publicado em 2010

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

Por Schotta, Gunnar, Sengupta, Roopsha, Kubicek, Stefan, Malin, Stephen, Kauer, Monika, Callén, Elsa, Celeste, Arkady, Pagani, Michaela, Opravil, Susanne, De La Rosa-Velazquez, Inti A., Espejo, Alexsandra, Bedford, Mark T., Nussenzweig, André, Busslinger, Meinrad, Jenuwein, Thomas
Publicado em 2008

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 gene

Por Perez, Carlos J., Mecklenburg, Lars, Jaubert, Jean, Santamaria, Lucia Martinez, Iritani, Brian M., Espejo, Alexsandra, Napoli, Eleonora, Song, Gyu, del Río, Marcela, DiGiovanni, John, Giulivi, Cecilia, Bedford, Mark T., Dent, Sharon Y.R., Wood, Richard D., Kusewitt, Donna F., Guénet, Jean Louis, Conti, Claudio J., Benavides, Fernando
Publicado no J Invest Dermatol (2015)