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Phosphorylation-dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex

ATP-dependent chromatin remodeling complexes such as INO80 have been implicated in checkpoint regulation in response to DNA damage. However, how chromatin remodeling complexes regulate DNA damage checkpoints remain unclear. Here, we identified a mechanism of regulating checkpoint effector kinase Rad...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Kapoor, Prabodh, Bao, Yunhe, Xiao, Jing, Espejo, Alexsandra, Yang, Lin, Bedford, Mark T., Peng, Guang, Shen, Xuetong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485934/
https://ncbi.nlm.nih.gov/pubmed/25959398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.03.032
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