Methylation by Set9 modulates FoxO3 stability and transcriptional activity

The FoxO family of transcription factors plays an important role in longevity and tumor suppression by regulating the expression of a wide range of target genes. FoxO3 has recently been found to be associated with extreme longevity in humans and to regulate the homeostasis of adult stem cell pools i...

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Bibliografiske detaljer
Main Authors: Calnan, Daniel R., Webb, Ashley E., White, Jamie L., Stowe, Timothy R., Goswami, Tapasree, Shi, Xiaobing, Espejo, Alexsandra, Bedford, Mark T., Gozani, Or, Gygi, Steven P., Brunet, Anne
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433933/
https://ncbi.nlm.nih.gov/pubmed/22820736
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