RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

Por Huang, Minzhou, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado no Arterioscler Thromb Vasc Biol (2007)

RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC

Por Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado em 2011

Immunotherapeutic suppression of IDO and tumor growth with ethyl pyruvate

Por Muller, Alexander J., DuHadaway, James B., Jaller, Daniel, Curtis, Peter, Metz, Richard, Prendergast, George C.
Publicado em 2010

CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL

Por Eldredge, Harriet Belding, DeNittis, Albert, DuHadaway, James B., Chernick, Michael, Metz, Richard, Prendergast, George C.
Publicado em 2013

1-Methyl-Tryptophan Synergizes with Methotrexate to Alleviate Arthritis in a Mouse Model of Arthritis

Por Pigott, Elizabeth, DuHadaway, James B., Muller, Alexander J., Gilmour, Susan, Prendergast, George C., Mandik-Nayak, Laura
Publicado no Autoimmunity (2014)

Zinc protoporphyrin-IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase

Por Metz, Richard, DuHadaway, James B., Rust, Sonja, Munn, David H., Muller, Alexander J., Mautino, Mario, Prendergast, George C.
Publicado em 2010

IDO2 modulates T cell-dependent autoimmune responses through a B cell-intrinsic mechanism

Por Merlo, Lauren M.F., DuHadaway, James B., Grabler, Samantha, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Publicado no J Immunol (2016)

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

Por Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Publicado em 2014

IDO1 is an Integral Mediator of Inflammatory Neovascularization

Por Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Publicado no EBioMedicine (2016)

Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

Por Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Publicado em 2008

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Por Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Publicado em 2012

The N-BAR Domain Protein, Bin3, Regulates Rac1- and Cdc42-Dependent Processes in Myogenesis

Por Simionescu-Bankston, Adriana, Leoni, Giovanna, Wang, Yanru, Pham, Peter P., Ramalingam, Arivudainambi, DuHadaway, James B., Faundez, Victor, Nusrat, Asma, Prendergast, George C., Pavlath, Grace K.
Publicado em 2013

Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors

Por Kumar, Sanjeev, Malachowski, William P., DuHadaway, James B., LaLonde, Judith M., Carroll, Patrick J., Jaller, Daniel, Metz, Richard, Prendergast, George C., Muller, Alexander J.
Publicado no J Med Chem (2008)

Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

Por Chang, Mee Young, Smith, Courtney, DuHadaway, James B, Pyle, Jennifer R, Boulden, Janette, Soler, Alejandro Peralta, Muller, Alexander J, Laury-Kleintop, Lisa D, Prendergast, George C
Publicado em 2011

The crystal structure of the BAR domain from human BIN1/ AMPHIPHYSIN II and its implications for molecular recognition

Por Casal, Eva, Federici, Luca, Zhang, Wei, Fernandez-Recio, Juan, Priego, Eva-Maria, Miguel, Ricardo Nuñez, DuHadaway, James B., Prendergast, George C., Luisi, Ben F., Laue, Ernest D.
Publicado em 2006

Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion

Por Muller, Alexander J., DuHadaway, James B., Chang, Mee Young, Ramalingam, Arivudinambi, Sutanto-Ward, Erika, Boulden, Janette, Soler, Alejandro P., Mandik-Nayak, Laura, Gilmour, Susan K., Prendergast, George C.
Publicado em 2010

Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

Por Huang, Yu-Hung, Peng, Weidan, Furuuchi, Narumi, DuHadaway, James B., Jimbo, Masaya, Pirritano, Andrea, Dunton, Charles J., Daum, Gary S., Leiby, Benjamin E., Brody, Jonathan R., Sawicki, Janet A.
Publicado no Oncotarget (2016)

O-Alkylhydroxylamines as Rationally-designed Mechanism-based Inhibitors of Indoleamine 2,3-Dioxygenase-1

Por Malachowski, William P., Winters, Maria, DuHadaway, James B., Lewis-Ballester, Ariel, Badir, Shorouk, Wai, Jenny, Rahman, Maisha, Sheikh, Eesha, LaLonde, Judith M., Yeh, Syun-Ru, Prendergast, George C., Muller, Alexander J.
Publicado no Eur J Med Chem (2015)

Targeted Disruption of the Murine Bin1/Amphiphysin II Gene Does Not Disable Endocytosis but Results in Embryonic Cardiomyopathy with Aberrant Myofibril Formation

Por Muller, Alexander J., Baker, Judith F., DuHadaway, James B., Ge, Kai, Farmer, George, Donover, P. Scott, Meade, Raymond, Reid, Christian, Grzanna, Reinhard, Roach, Arthur H., Shah, Neelima, Soler, Alejandro Peralta, Prendergast, George C.
Publicado em 2003

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

Por Metz, Richard, Smith, Courtney, DuHadaway, James B., Chandler, Phillip, Baban, Babak, Merlo, Lauren M. F., Pigott, Elizabeth, Keough, Martin P., Rust, Sonja, Mellor, Andrew L., Mandik-Nayak, Laura, Muller, Alexander J., Prendergast, George C.
Publicado no Int Immunol (2014)