RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

по Huang, Minzhou, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Опубликовано в: Arterioscler Thromb Vasc Biol (2007)

Discovery of IDO1 inhibitors: from bench to bedside

по Prendergast, George C., Malachowski, William P., DuHadaway, James B., Muller, Alexander J.
Опубликовано в: Cancer Res (2017)

RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC

по Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Опубликовано 2011

Immunotherapeutic suppression of IDO and tumor growth with ethyl pyruvate

по Muller, Alexander J., DuHadaway, James B., Jaller, Daniel, Curtis, Peter, Metz, Richard, Prendergast, George C.
Опубликовано 2010

CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL

по Eldredge, Harriet Belding, DeNittis, Albert, DuHadaway, James B., Chernick, Michael, Metz, Richard, Prendergast, George C.
Опубликовано 2013

1-Methyl-Tryptophan Synergizes with Methotrexate to Alleviate Arthritis in a Mouse Model of Arthritis

по Pigott, Elizabeth, DuHadaway, James B., Muller, Alexander J., Gilmour, Susan, Prendergast, George C., Mandik-Nayak, Laura
Опубликовано в: Autoimmunity (2014)

Zinc protoporphyrin-IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase

по Metz, Richard, DuHadaway, James B., Rust, Sonja, Munn, David H., Muller, Alexander J., Mautino, Mario, Prendergast, George C.
Опубликовано 2010

IDO2 modulates T cell-dependent autoimmune responses through a B cell-intrinsic mechanism

по Merlo, Lauren M.F., DuHadaway, James B., Grabler, Samantha, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Опубликовано в: J Immunol (2016)

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

по Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Опубликовано 2014

IDO1 is an Integral Mediator of Inflammatory Neovascularization

по Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Опубликовано в: EBioMedicine (2016)

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

по Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Опубликовано в: Dis Model Mech (2017)

Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

по Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Опубликовано 2008

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

по Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Опубликовано 2012

Therapeutic Antibody Targeting of Indoleamine-2,3-Dioxygenase (IDO2) Inhibits Autoimmune Arthritis

по Merlo, Lauren M.F., Grabler, Samantha, DuHadaway, James B., Pigott, Elizabeth, Manley, Kaylend, Prendergast, George C., Laury-Kleintop, Lisa D., Mandik-Nayak, Laura
Опубликовано в: Clin Immunol (2017)

The N-BAR Domain Protein, Bin3, Regulates Rac1- and Cdc42-Dependent Processes in Myogenesis

по Simionescu-Bankston, Adriana, Leoni, Giovanna, Wang, Yanru, Pham, Peter P., Ramalingam, Arivudainambi, DuHadaway, James B., Faundez, Victor, Nusrat, Asma, Prendergast, George C., Pavlath, Grace K.
Опубликовано 2013

Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors

по Kumar, Sanjeev, Malachowski, William P., DuHadaway, James B., LaLonde, Judith M., Carroll, Patrick J., Jaller, Daniel, Metz, Richard, Prendergast, George C., Muller, Alexander J.
Опубликовано в: J Med Chem (2008)

Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

по Chang, Mee Young, Smith, Courtney, DuHadaway, James B, Pyle, Jennifer R, Boulden, Janette, Soler, Alejandro Peralta, Muller, Alexander J, Laury-Kleintop, Lisa D, Prendergast, George C
Опубликовано 2011

The crystal structure of the BAR domain from human BIN1/ AMPHIPHYSIN II and its implications for molecular recognition

по Casal, Eva, Federici, Luca, Zhang, Wei, Fernandez-Recio, Juan, Priego, Eva-Maria, Miguel, Ricardo Nuñez, DuHadaway, James B., Prendergast, George C., Luisi, Ben F., Laue, Ernest D.
Опубликовано 2006

Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion

по Muller, Alexander J., DuHadaway, James B., Chang, Mee Young, Ramalingam, Arivudinambi, Sutanto-Ward, Erika, Boulden, Janette, Soler, Alejandro P., Mandik-Nayak, Laura, Gilmour, Susan K., Prendergast, George C.
Опубликовано 2010

Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

по Huang, Yu-Hung, Peng, Weidan, Furuuchi, Narumi, DuHadaway, James B., Jimbo, Masaya, Pirritano, Andrea, Dunton, Charles J., Daum, Gary S., Leiby, Benjamin E., Brody, Jonathan R., Sawicki, Janet A.
Опубликовано в: Oncotarget (2016)